Chapter 18
Chapter 18
Chapter 18
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Hepadnaviruses- HBV<br />
• circular, partial dsDNA genome<br />
• transcribed by host RNAP<br />
• generates several mRNA molecules<br />
• one for pregenome RNA<br />
• others encode polymerase with reverse<br />
transcriptase activity<br />
• pregenome converted to dsDNA by virus polymerase<br />
(+RNA -DNA 2S DNA)<br />
11