Chapter 18
Chapter 18
Chapter 18
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Inheritable CJD- prnp<br />
• A Gerstmann-Straussier-Scheinker syndrome<br />
• A Kuru like familial disease Inherited forms<br />
emerge earlier (~ 45 yr)<br />
• familial CJD, GSS, fatal familial insomnia (FFI)-<br />
10~15%<br />
• specific mutation of the gene on chromosome 20-<br />
prnp