Dr. Soojin Ryu 12/03/1971, Seoul, Korea CURRICULUM ... - HBIGS

Dr. Soojin Ryu
Max Planck Institute for Medical Research
-Developmental Genetics of Nervous System-
Jahnstraße 29, 69120 Heidelberg, Germany
Tel: +49 6221 486 210
email: soojin.ryu@mpimf-heidelberg.mpg.de
12/03/1971, Seoul, Korea
CURRICULUM VITAE
since 2008 Group Leader, Indepedent Junior Research Group, Max Planck Institute
for Medical Research, Heidelberg
2000 - 2007 Postdoctoral Research: Department of Developmental Biology, University
of Freiburg, Germany, (in the laboratory of Dr. Wolfgang Driever)
1995 - 1999 PhD, Department of Molecular and Cell Biology, University of California,
Berkeley, CA, USA, (graduate adviser: Dr. Robert Tjian)
1990 - 1995 B.A. in Biology, Magnum Cum Laude, Harvard University
HONORS AND FELLOWSHIPS
2000-2003 Human Frontiers Science Program Postdoctoral Fellowship
2000 Alexander von Humboldt Foundation Postdoctoral Fellowship
1995-2000 Howard Hughes Medical Institute Predoctoral Fellowship
1994 John Harvard Award for Academic Excellence
FIELDS OF INTEREST
Hypothalamus Development, Zebrafish genetics, genetic regulatory network, neural circuitry
formation, Stress response
PUBLICATIONS :
Filippi, A., Duerr, K., Ryu, S. Willaredt, M., Holzschuh, J., Driever, W. (2007)
Expression and function of nr4a2, lmx1b, and pitx3 in zebrafish dopaminergic and
noradrenergic neuronal development. BMC Dev Biol. 7:135
Ryu, S., Mahler, J., Acampora, D., Holzschuh, J. Erhardt, S., Simeone, A., and Driever,
W. (2007) Orthopedia homeodomain protein is essential for diencephalic dopaminergic
neuron development. Current Biology. 17 (10): 873-80.
Brochschmidt, A., Todt, U., Ryu, S., Hoischen, A., Landwehr, C., Birnbaum, S.,
Frenck, W., Radlwimmer, B., Lichter, P., Engels, H., Driever, W., Kubisch, C., Weber
R. G. (2007) Severe mental retardation with breathing abnormalities (Pitt-Hopkins
syndrome) is caused by haploinsufficiency of the neuronal bHLH transcription factor
TCF4. Hum. Mol. Genet. 15;16(12):1488-94.

Ryu, S., Holzschuh, J. Mahler, J. and Driever, W. (2006) Genetic analysis of
Dopaminergic system development in zebrafish. J. Neural. Transm. Suppl. 70: 61-66.
Review.
Ryu, S., and Driever, W. (2006) Minichromosome maintenance proteins as markers for
proliferation zones during embryogenesis. Cell Cycle. 11:1140-1142. Review.
Chapouton, P., Adolf, B., Leucht, C., Tannhauser, B., Ryu, S., Driever, W., and Bally-
Cuif, L. (2006) her5 expression reveals a pool of neural stem cells in the adult zebrafish
midbrain. Development. 133:4293-4303.
Durr, K., Holzschuh, J., Filippi, A., Ettl, A.K., Ryu, S., Shepherd, I.T., and Driever,
W. (2006) Differential roles of transcriptional mediator complex subunits
Crsp34/Med27, Crsp150/Med14, and Trap100/Med24 during zebrafish retinal
development. Genetics. 174:693-705.
Ryu, S., Holzschuh, J., Erhardt, S., Ettl, A.K., and Driever, W. (2005) Depletion of
minichromosome maintenance protein 5 in zebrafish retina causes cell-cycle defect and
apoptosis. Proc. Natl. Acad. Sci. USA. 102: 18467-18472.
Holzschuh, J., Ryu, S., Aberger, F., and Driever, W. (2001) Dopamine transporter
expression distinguishes dopaminergic neurons from other catecholaminergic neurons
in the developing zebrafish embryo. Mech. Dev. 101(1-2): 237-243
Ryu, S., Zhou, S., Laudrner, A.G., and Tjian, R. (1999). Transcriptional cofactor
complex CRSP is required for activity of the enhancer-binding protein Sp1. Nature.
397:446-450.
Ryu, S. and Tjian, R. (1999). Purification of the transcription cofactor complex CRSP.
Proc. Natl. Acad. Sci. USA. 96: 7137-7142
Näär, A.M., Ryu, S., and Tjian, R. (1999). Co-factor requirements for transcriptional
activation by Sp1. Introductory Chapter. Cold Spring Harbor Symposia on Quantitative
Biology: Mechanisms of Transcription. 63:189-199. Review.