Vicki Wheelock MD HDSA Center of Excellence at UC Davis ...

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2008: First drug approved by FDA for HD Tetrabenazine (TETRA study) • Double-blind, placebocontrolled study <strong>of</strong> tetrabenazine in manifest HD • 84 people with HD, randomized 2:1 to TBZ or placebo for 12 weeks • Primary endpoint: chorea score 24
Results: Tetrabenazine H · S · G Huntington · Study · Group 25
Page 1 and 2: Vicki Wheelock MD HDSA Center of Ex
Page 3 and 4: Presenter Disclosures Dr. Vicki Whe
Page 5 and 6: Clinical research studies, especial
Page 7 and 8: The pathway to finding new drugs Pr
Page 9 and 10: What are double blind, randomized,
Page 11 and 12: Who can participate in clinical tri
Page 13 and 14: How much time is required? • Stud
Page 15 and 16: What kinds of activities take place
Page 17 and 18: What kinds of activities take place
Page 19 and 20: What about privacy? • Confidentia
Page 21 and 22: Current observational studies Study
Page 23: The HD Pipeline Source: Marsha Mill
Page 27 and 28: Getting involved in research: Five
Page 29 and 30: There are reasons for and against v
Page 31 and 32: COHORT COHORT • Cooperative Hunti
Page 33 and 34: • Sponsor: NIH PREDICT study •
Page 36 and 37: 2CARE Study • Sponsor: NIH, Phase
Page 38 and 39: HART trial • Sponsor: Neurosearch
Page 40 and 41: CREST-E study • Sponsor: NIH, Pha
Page 42: H · S · G Huntington · Study ·

Vicki Wheelock MD HDSA Center of Excellence at UC Davis ...

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