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Vicki Wheelock MD HDSA Center of Excellence at UC Davis ...

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Wh<strong>at</strong> are observ<strong>at</strong>ional trials?<br />

• These are studies involving humans th<strong>at</strong> follow<br />

research participants over time without making a<br />

tre<strong>at</strong>ment intervention.<br />

• Observ<strong>at</strong>ional studies allow researchers to study<br />

the progression <strong>of</strong> HD over time in a number <strong>of</strong><br />

individuals, and help us to understand the<br />

symptoms people experience, the signs noticed<br />

by investig<strong>at</strong>ors <strong>at</strong> the sites, the r<strong>at</strong>e <strong>of</strong><br />

progression, and sometimes markers <strong>of</strong> HD such<br />

as brain scan or blood test changes.

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