Lect. 5 Host Pathogen interaction-II
Lect. 5 Host Pathogen interaction-II
Lect. 5 Host Pathogen interaction-II
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. RPS2 is an NB-LRR protein that resides at the<br />
plasma membrane. It is activated by the AvrRpt2<br />
cysteine protease type <strong>II</strong>I effector from P.<br />
syringae. Auto-processing of AvrRpt2 by a host<br />
cyclophilin reveals a consensus, but<br />
unconfirmed, myristoylation site at the new<br />
amino terminus, suggesting that it might also be<br />
localized to the host plasma membrane. AvrRpt2<br />
is the third effector that targets RIN4. Cleavage<br />
of RIN4 by AvrRpt2 leads to RPS2-mediated<br />
ETI. In the absence of RPS2, AvrRpt2<br />
presumably cleaves RIN4 and other targets as<br />
part of its virulence function.
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