Lect. 5 Host Pathogen interaction-II

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Guard Hypothesis 1. (A) A cellular complex of proteins (blue), which includes both the ‘guardee’ molecule (red) and a resistance gene 2. (B) Binding of the effector to its target results in dissociation and activation of R-gene and thus disease resistance. 3. (C) Alternatively, the R-gene may not be part of the target complex until effector binding. 4. (D) Recruitment to the effector/target complex would then activate the R-gene.
Elicitor Target R-gene (Vander Biezen and Jones, 1998. Current Biology)
Page 1 and 2: Host-Pathogen interaction-II Pl Pat
Page 3: GUARD HYPOTHESIS Vander Biezen and
Page 7 and 8: DIFFERENT INDIRECT MODELS TO SUPPOR
Page 9 and 10: 2. Matchmaker : • Effector induce
Page 11 and 12: Affinity enhancement : • Interact
Page 13 and 14: De-repression : • Effector derepr
Page 15 and 16: Dual recognition • This model in
Page 17 and 18: RECENT EXAMPLES OF PLANT-PATHOGEN I
Page 19 and 20: . RPS2 is an NB-LRR protein that re
Page 21 and 22: Arabidopsis-P. syringae system B. R
Page 23 and 24: Contd… Arabidopsis-P. syringae sy
Page 25 and 26: E. The transmembrane RLP Cf-2 guard

Lect. 5 Host Pathogen interaction-II

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