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July 3 (2008) - Helsinki Institute of Physics

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RAPSODI:<br />

SiPM development for applied<br />

research in radiation<br />

protection<br />

Fabio Risigo<br />

Universita’ dell’Insubria in Como (Italy)<br />

on behalf <strong>of</strong><br />

The RAPSODI collaboration<br />

10 th iWoRiD, <strong>Helsinki</strong> June 29 – <strong>July</strong> 3, <strong>2008</strong>


RAPSODI: RAdiation Protection with<br />

Silicon Optoelectronic Devices and<br />

Instruments<br />

Funded by the EC under the Sixth Framework Program (Co-operative research)<br />

Start-time Oct 2006; End-time Jan 2009<br />

Main objectives: Silicon Photo Multipliers development and optimization for three<br />

well defined applications: Dosimetry in Mammography, Radon Monitoring, illicit<br />

traffic <strong>of</strong> radioactive material (homeland security)<br />

4 Small and Medium Enterprises + 3 R&D performers<br />

SensL (IE)<br />

Specialized in SiPM development<br />

PTW (DE)<br />

Leader in EU market <strong>of</strong> radiation monitor & dosimeter<br />

Plch SMM (CZ)<br />

Leader in Radon meter construction<br />

ForimTech (CH)<br />

Small start-up with a focus on photon sensing<br />

technologies and detectors assembly<br />

UNICO (IT)<br />

Leading partner<br />

AGH (PL)<br />

Microelectronic <strong>Institute</strong><br />

ITEP (RU)<br />

Long standing tradition in SiPM<br />

Significant characterization parameters <strong>of</strong> SiPM and the dosimetry measurements in mammography<br />

10 th iWoRiD, <strong>Helsinki</strong> June 29 – <strong>July</strong> 3, <strong>2008</strong>


Silicon Photon Multiplier<br />

SiPM = High density (~10 3 /mm 2 ) matrix <strong>of</strong> diodes with a common output, working in<br />

Geiger-Müller regime<br />

advantages over traditional photo-detectors:<br />

<br />

<br />

<br />

high sensitivity (single photon discrimination)<br />

high speed (T rise<br />

~ 1 ns; T fall<br />

~ 50 ns)<br />

compactness, robustness, low operating<br />

voltage and power consumption, low cost<br />

Matrix <strong>of</strong> binary elements allows an analog<br />

measurement, counting the number <strong>of</strong> hit cells<br />

Producer<br />

Area (mm 2 )<br />

Pixel size<br />

(µm)<br />

No. cells<br />

V working<br />

DCR<br />

GAIN<br />

PDE (%)<br />

(green)<br />

SensL<br />

3 x 3<br />

20 x 20<br />

8640<br />

30<br />

6 MHz<br />

10 6<br />

10<br />

Hamamatsu<br />

1 x 1<br />

17 x 14<br />

1600<br />

77<br />

220 kHz<br />

3 x 10 5<br />

20<br />

CPTA<br />

1 x 1<br />

30 x 30<br />

500<br />

24<br />

3 MHz<br />

10 6<br />

30<br />

SensL is developing custom oriented SiPM<br />

10 th iWoRiD, <strong>Helsinki</strong> June 29 – <strong>July</strong> 3, <strong>2008</strong>


Full characterization protocol<br />

<br />

<br />

<br />

<br />

I-V measurements (leakage current, quenching resistor, breakdown voltage)<br />

Noise measurements (vs over voltage and vs temperature):<br />

<br />

<br />

dark counting rate (DCR) vs bias voltage<br />

optical cross-talk (DCR vs threshold)<br />

Analysis <strong>of</strong> (Poissonian photon) spectrum (vs temperature)<br />

<br />

<br />

<br />

<br />

resolution power (how many photons can I distinguish?) & gain<br />

working point optimization (at low and large flux)<br />

noise measurement (not DCR)<br />

optical cross-talk (deviations from the Poissonian distribution)<br />

linearity & dynamic range<br />

Spectral response (PDE vs , PDE vs temperature)<br />

<br />

timing properties and time resolution (not relevant for RAPSODI but in progress)<br />

10 th iWoRiD, <strong>Helsinki</strong> June 29 – <strong>July</strong> 3, <strong>2008</strong>


Photon Spectrum & Gain<br />

Light source: Pico Quant PDL 800 - light at ~ 510 nm (green)<br />

G<br />

= ∆<br />

peak −<br />

QDC<br />

e ⋅ k<br />

cal<br />

AMP<br />

peak<br />

<br />

<br />

<br />

good resolution power<br />

Gain<br />

Noise (NOT DCR!)<br />

measurement (width <strong>of</strong><br />

single pulse)<br />

width count<br />

> 20 peaks<br />

10 th iWoRiD, <strong>Helsinki</strong> June 29 – <strong>July</strong> 3, <strong>2008</strong>


Dark Count Rate & X talk<br />

DCR @ different thresholds on the output signal to be digitalized<br />

Dark Counting Rate (DCR) is the<br />

rate at which a Geiger avalanche is<br />

randomly initiated by thermal<br />

emission.<br />

> 0.5 ph<br />

> 1.5 ph<br />

Threshold scan<br />

0.5 ph<br />

1.5 ph<br />

2.5 ph<br />

DCR @ fixed threshold (0.5 phe-)<br />

> 2.5 ph<br />

Increasing the bias, the GM probability increases<br />

10 th iWoRiD, <strong>Helsinki</strong> June 29 – <strong>July</strong> 3, <strong>2008</strong><br />

the avalanche generation can generate an<br />

avalanche in a near cell through a photon;<br />

measuring the DCR for different thresholds is<br />

possible to define and evaluate the Optical<br />

Cross talk as:<br />

X talk<br />

=<br />

DCR(1.5<br />

ph)<br />

DCR(0.5<br />

ph)


Photon Detection Efficiency<br />

n<br />

_ cell<br />

=<br />

n<br />

ph<br />

⋅ QE<br />

⋅<br />

FillFactor<br />

⋅<br />

p<br />

GM<br />

PDE<br />

Pico Quant<br />

PDL 800<br />

Ligth guide<br />

Ø 1 mm<br />

clear fiber<br />

(divergence 15°)<br />

FC<br />

connector<br />

SiPM<br />

sensor<br />

Light calibrated against PMT (H5783) and<br />

tuned to have 200 ph/burst<br />

FC to guarantees the reproducibility <strong>of</strong> the fiber tip to SiPM<br />

surface distance and alignment (acceptance control)<br />

The PDE has to be corrected for the<br />

Optical Cross Talk as:<br />

n = n ⋅ 1+<br />

_ meas<br />

_ cell<br />

( X )<br />

talk<br />

10 th iWoRiD, <strong>Helsinki</strong> June 29 – <strong>July</strong> 3, <strong>2008</strong>


Temperature Dependence<br />

Pico Quant PDL 800 – light @ ~ 510 nm<br />

Cooling Box + Temperature control<br />

Gain vs bias voltage<br />

Gain vs temperature<br />

for any specific working conditions you have a non trivial depend on the<br />

temperature, due to the variation <strong>of</strong> the V BD<br />

(against temperature)<br />

re-scaling the<br />

breakdown<br />

voltage<br />

dV<br />

V<br />

BD<br />

= ( T −TRT<br />

) + V<br />

dT<br />

RT<br />

normalizing all the measurements, you obtain a remarkable linear<br />

dependence against over voltage and a very little spread vs temperature<br />

Gain independent from<br />

temperature as function <strong>of</strong><br />

over voltage<br />

Results particularly important once you have to guarantee the stability <strong>of</strong> an instrument as the environmental<br />

conditions change<br />

10 th iWoRiD, <strong>Helsinki</strong> June 29 – <strong>July</strong> 3, <strong>2008</strong>


An Application: Dosimetry in<br />

mammography<br />

Dosimetry in mammography is<br />

utmost important and this is<br />

somehow proven by the ongoing<br />

debate on the relevance <strong>of</strong><br />

mammography screening<br />

…but currently existing<br />

instruments are limited:<br />

Standard Termo-Luminescent<br />

Detectors require to be analyzed after<br />

examination, degrade with time<br />

MOSFET detectors suffer from low<br />

stability and degrade with each irradiation<br />

Ionization chamber devices need<br />

relatively high voltage (cannot be used in<br />

contact with the patient), not tissue<br />

equivalent<br />

10 th iWoRiD, <strong>Helsinki</strong> June 29 – <strong>July</strong> 3, <strong>2008</strong><br />

precise measurements <strong>of</strong> the<br />

actual dose being received by a<br />

patient without distorting the X-ray<br />

beam and introducing any<br />

artefacts in the image<br />

Some functional requirements:<br />

dose rate range (2 ÷ 150 mGy/s)<br />

dose range minimum (0.5 mGy)<br />

sensitivity (5%)<br />

overall accuracy (±10%)<br />

tolerance to environmental<br />

variation & stability


The Prototype<br />

Designed and tested prototype @ PTW – secondary standard lab for dosimetry:<br />

Scintillator<br />

(tile or fiber)<br />

Ligth guide<br />

Ø 1 mm<br />

clear fiber<br />

FC connector &<br />

SiPM<br />

Electronics<br />

PHISYCAL OBSERVABLE:<br />

“buffered” signal sum<br />

Sum <strong>of</strong> samples signals selected<br />

by an edge detector algorithm + left<br />

& right buffer<br />

-> proportional to the DOSE<br />

Trace plot: typical mammo SiPM output<br />

(continuous photons flux – pulse duration <strong>of</strong> each sample100 ms)<br />

BUFFERED<br />

SUM<br />

10 th iWoRiD, <strong>Helsinki</strong> June 29 – <strong>July</strong> 3, <strong>2008</strong><br />

~TIME


Result summary<br />

Two different set-up (optimized for dynamic range & ):<br />

1mm scintillator tile coupled with SensL SiPM (9k cells, 3x3 mm 2 )<br />

Blue scintillator fiber coupled with Hamamatsu (400 cells, 1x1 mm 2 )<br />

Irradiation: 0,22 ÷ 217 mGy/s<br />

Tile +<br />

SensL<br />

Fiber +<br />

Hamamatsu<br />

Precision(%)<br />

1.95 ± 0.05<br />

2.31 ± 0.03<br />

Sensitivity A<br />

(mGy/s)<br />

2.60 ± 0.05<br />

2.05 ± 0.03<br />

MDS B (mGy/s)<br />

0.524 ± 0.009<br />

0.458 ± 0.007<br />

Linear<br />

Dinamic range<br />

(mGy/s)<br />

160<br />

> 200<br />

A<br />

Sensitivity: Precision / system gain<br />

B<br />

MDS: minimum signal distinguishable from the noise<br />

10 th iWoRiD, <strong>Helsinki</strong> June 29 – <strong>July</strong> 3, <strong>2008</strong>


Conclusions<br />

<br />

<br />

<br />

Within the RAPSODI project, a laboratory for SiPM and light sensors<br />

characterization has been setup at the University <strong>of</strong> Insubria. The lab<br />

has developed both the expertise and the instrumentation to perform<br />

all the measurements to fully characterize SiPM.<br />

This expertise has been used also in the test <strong>of</strong> a mammography<br />

dosimeter instrument being developed in collaboration with PTW.<br />

The performances <strong>of</strong> the first MammoDos prototype are according to<br />

specification and this will lead to the final product before the end <strong>of</strong><br />

the project.<br />

! THANK YOU !<br />

10 th iWoRiD, <strong>Helsinki</strong> June 29 – <strong>July</strong> 3, <strong>2008</strong>


Backup slides


Temperature Dependence<br />

SensL 9k: 23.2 mV/°C ± 1.4 mV/°C<br />

Gain independent from<br />

temperature<br />

as function <strong>of</strong> over voltage


Equipment<br />

• USB-VME Bridge CAEN<br />

• V171816ch QDC CAEN V792N<br />

• DC power supply Agilent 6645A<br />

• Scope Agilent 54624A<br />

• Pulse Generator Agilent 33250A [50 MHz]<br />

• Lecroy 821 NIM discriminator<br />

• CAEN NIM level translators<br />

• SensL Board + ZFL-500-BNC [20 dB gain]<br />

• PDL800-B PicoQuant (green LED)<br />

• OZ optics coupler & focuser<br />

• Dark Box +XY stage and manual Z<br />

• Keithley 4200 SCA<br />

• 590 + 595 C-V meters QS+HF


RAPSODI project<br />

<br />

<br />

<br />

Real-time dosimeter for mammography (MAMMODOS): design, construction and<br />

commissioning <strong>of</strong> a real-time instruments to measure the dose released to the breast<br />

during a mammographic procedure.<br />

Apparatus conceptual design, study <strong>of</strong> the interaction <strong>of</strong> X-ray with plastic plate,<br />

dedicated SiPMs Electronics Development & production, first prototype construction and<br />

characterisation and s<strong>of</strong>tware development, final system integration with dedicated SiPM<br />

and laboratory and hospital tests.<br />

Radon concentration meter (RADONPROBE): design, construction and commissioning<br />

<strong>of</strong> a portable real-time detector for Radon indoor and water concentration measurements.<br />

Apparatus conceptual design, gas collector & measuring chamber study, dedicated<br />

electronics and s<strong>of</strong>tware development, construction and characterization <strong>of</strong> the Radon<br />

Probe first prototype and preliminary quality assessment, system integration with<br />

dedicated SiPMs and qualification tests.<br />

Portable radioactivity monitor (MICROSNOOPER): design, construction and<br />

commissioning <strong>of</strong> a very small and cheap portable real-time device to detect and identify<br />

any type <strong>of</strong> radiation.<br />

Apparatus conceptual design, study <strong>of</strong> the interaction <strong>of</strong> different types <strong>of</strong> radiation with<br />

the scintillator, development and tests <strong>of</strong> the prototype device, development and<br />

production <strong>of</strong> a dedicated integrated circuit, development <strong>of</strong> the s<strong>of</strong>tware for device<br />

control and construction qualification and tests <strong>of</strong> the MICROSNOOPER prototype.


I-V measurements<br />

Remarks:<br />

quenching resistor<br />

breakdown voltage<br />

leakage current<br />

DCR


One Application: Dosimetry in<br />

mammography<br />

Real-time dosimetry in mammography: development <strong>of</strong> a dose-meter for<br />

mammography (MAMMODOS), which will allow real time and precise<br />

measurements <strong>of</strong> the actual dose being received by a patient without distorting the<br />

X-ray beam and introducing any artefacts in the image<br />

Mammography is the process <strong>of</strong> using low-dose X-rays (usually around 0.7 mSv) to examine<br />

the human breast. It is used to look for different types <strong>of</strong> tumors, cysts and micro-calcifications.<br />

Existing devices:<br />

Standard Thermo-Luminescent Detectors: they required to be analyzed after the examination;<br />

they degrade with time and need regular replacement (time consuming calibration procedure);<br />

furthermore, since they tend to be positioned upstream <strong>of</strong> the object, they create artifacts on the<br />

image.<br />

MOSFET detectors: they suffer from low stability and degrade with each irradiation. Being<br />

positioned upstream the object they also create artifacts on the image.<br />

Ionization chamber devices: they do not suffer <strong>of</strong> any degradation effect, their outputs is<br />

reliable and stable, but they need relatively high voltage and therefore cannot be used in contact<br />

with the patient during examination, besides that they are definitely not tissue-equivalent.


One Application: Dosimetry in<br />

mammography<br />

SetUp: scintillator (Tile or<br />

Filer) coupled with SiPM<br />

Trace plot: typical mammo SiPM output<br />

(continuous photons flux – pulse duration 100 ms)<br />

boundary conditions:<br />

dose range rate<br />

minimum detectable signal<br />

sensitivity<br />

overall accuracy<br />

Tolerance to environmental variation<br />

& stability<br />

SIGNAL region<br />

PEDESTAL region<br />

~TIME<br />

Numeri e plot linearita’<br />

Minimum Signal Distinguishable from the noise floor ~0.5 mGy/s<br />

Sensitivity ~2 mGy/s

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