From Mind To Market - Boehringer Ingelheim

8
We know every step of the way
Genetic engineering
- Proprietary expression plasmids
- Efficient regulatory sequences
- High amplification
- Short cloning times
- Stable host vector system
There is no substitute for experience. At Boehringer
Ingelheim we have been directly involved with
commercial biotechnology for over one hundred
years. In every decade of our history we have
demonstrated an understanding of current technology,
the ability to recognize its new opportunities
and the corporate capacity to exploit them.
Very often we have lead the way developing new
techniques and manufacturing processes.
Cell-line development
- Suspension adapted host cell-line
- Adaptation to protein-free media
- Autocrine cell-lines
- Short generation times
- Cell banking (MCB/WCB)
Fermentation
- Media design
- Feeding strategy
- Process optimization
- Facilitated scale-up
- Large-scale cGMP
Downstream processing
- Refolding procedures
- Expanded bed chromatography
- Chromatography
- Ultrafiltration / diafiltration
- Microwave virus inactivation