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CLASSIFICATION OF LUNG CANCER, Cl inical manifestations OF LUNG CANCER

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<strong>CLASSIFICATION</strong> <strong>OF</strong> <strong>LUNG</strong> <strong>CANCER</strong>, <strong>Cl</strong><strong>inical</strong> ma...<br />

by garest - http://garest.net/classification-of-lung-cancer-cl<strong>inical</strong>-<strong>manifestations</strong>-of-lung-cancer.html<br />

<strong>CLASSIFICATION</strong> <strong>OF</strong> <strong>LUNG</strong> <strong>CANCER</strong>, <strong>Cl</strong><br />

<strong>inical</strong> <strong>manifestations</strong> <strong>OF</strong> <strong>LUNG</strong> <strong>CANCER</strong><br />

<strong>CLASSIFICATION</strong> <strong>OF</strong> <strong>LUNG</strong> <strong>CANCER</strong>, <strong>Cl</strong><strong>inical</strong> <strong>manifestations</strong> <strong>OF</strong> <strong>LUNG</strong> <strong>CANCER</strong><br />

<strong>LUNG</strong> <strong>CANCER</strong> is a malignancy of the lung tissue, Lung cancer is an abnormality of the cells –<br />

cells undergoing proliferation in the lungs<br />

<strong>CLASSIFICATION</strong> <strong>OF</strong> <strong>LUNG</strong> <strong>CANCER</strong><br />

<strong>Cl</strong>assification according to WHO Pleura and Lung Neoplasms – Lung (1977):<br />

1. Bronkogenik carcinoma.<br />

a. Epidermoid carcinoma (carcinoma).<br />

Cancer is derived from the surface of the bronchial epithelium. Epithelial changes including<br />

metaplasia or dysplasia caused by long-term smoking, typically precedes the onset of tumors.<br />

Centrally located around the hilum, and protruding into the major bronchi. Diameter tumors<br />

rarely exceed a few centimeters and are likely to spread directly to the hilar lymph nodes, chest<br />

wall and mediastinum.<br />

b. Small cell carcinoma (oat cell included).<br />

Usually located around the middle of the main branches arising from this bronki.Tumor cells –<br />

Kulchitsky cells, the normal component of the bronchial epithelium. Formed out of the cell – a<br />

small cell with a nucleus and cytoplasm concentrated hiperkromatik bit. Early metastasis to the<br />

mediastinal and hilar lymph nodes, as well as haematogenous spread to the organs – organs<br />

distal.<br />

c. Adenocarcinoma (including alveolar cell carcinoma).<br />

Cellular arrangement shows such as bronchial glands and may contain mucus. Most arise in<br />

the peripheral bronchial segments and sometimes – sometimes can be associated with local<br />

scarring of the lungs – pulmonary and chronic interstitial fibrosis. Lesions often spread through<br />

the blood and lymph vessels in the early stages, and still do not show cl<strong>inical</strong> symptoms –<br />

symptoms until the occurrence of distant metastases.<br />

d. Large cell carcinoma.<br />

Is a cell – malignant cells were large and very poorly differentiated with a large cytoplasm and<br />

nucleus size wide – range. Cells – these cells are likely to arise in the lung tissue – peripheral<br />

lung, grows quickly with extensive and rapid deployment to places – places far away.<br />

e. Combined adenocarcinoma and epidermoid.<br />

f. Others – others.<br />

1). Carcinoid tumors (bronchial adenoma).<br />

2). Bronchial gland tumors.<br />

3). Papillary tumors of the epithelial surface.<br />

4). Tumor mix and Karsinosarkoma<br />

5). Sarcoma<br />

6). Not classified.<br />

7). Mesotheliomas.<br />

8). Melanoma.<br />

(Price, Pathophysiology, 1995).<br />

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<strong>CLASSIFICATION</strong> <strong>OF</strong> <strong>LUNG</strong> <strong>CANCER</strong>, <strong>Cl</strong><strong>inical</strong> ma...<br />

by garest - http://garest.net/classification-of-lung-cancer-cl<strong>inical</strong>-<strong>manifestations</strong>-of-lung-cancer.html<br />

<strong>Cl</strong><strong>inical</strong> <strong>manifestations</strong> <strong>OF</strong> <strong>LUNG</strong> <strong>CANCER</strong><br />

1. Early symptoms.<br />

Local stridor and dyspnea possibly due to mild bronchial obstruction.<br />

2. Common symptoms.<br />

a. Cough<br />

Possible due to the irritation caused by the tumor mass. Cough started as a dry cough without<br />

sputum form, but evolved to the point where the molded thick and purulent sputum in the<br />

respond to secondary infections.<br />

b. Hemoptysis<br />

Sputum blushed because sputum blood through the surface ulcerated tumors.<br />

c. Anorexia, fatigue, weight loss.<br />

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