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σ70 binds both the –35 and –10 sequences.<br />
The crystal structure of a sigma factor fragment from the<br />
bacterium Thermus aquaticus shows that these regions fold into<br />
three independent domains in the protein:<br />
domain σ2 contains 1.2-2.4, σ3 contains 3.0-1.3, and σ4 contains<br />
4.1-4.2<br />
B-22