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Brochure 1 - The School of Molecular and Cellular Biology ...

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Graduate Application Information<br />

<strong>Molecular</strong> <strong>and</strong> Integrative Physiology (MIP)<br />

To apply to the Department <strong>of</strong> <strong>Molecular</strong> <strong>and</strong> Integrative Physiology<br />

at the University <strong>of</strong> Illinois at Urbana-Champaign, apply to the<br />

<strong>School</strong> <strong>of</strong> <strong>Molecular</strong> <strong>and</strong> Cell <strong>Biology</strong>. Indicate on your application<br />

that you are interested in physiology. Students are supported in the<br />

first semester by the <strong>School</strong> <strong>and</strong> rotate through the labs <strong>of</strong> three <strong>of</strong><br />

the more than 80 faculty in the <strong>School</strong> before selecting their thesis<br />

advisor. Information <strong>and</strong> application forms are available at www.<br />

mcb.uiuc.edu/graduate/gradprospect.html.<br />

<strong>Molecular</strong> <strong>and</strong><br />

Integrative Physiology<br />

University <strong>of</strong> Illinois at Urbana-Champaign<br />

Medical Scholars Program (MSP)<br />

<strong>The</strong> Medical Scholars Program at the University <strong>of</strong> Illinois at Urbana-<br />

Champaign has over 150 MD/JD <strong>and</strong> MD/PhD students pursuing<br />

graduate study in over 35 academic disciplines. Information <strong>and</strong><br />

application forms are available at www.med.uiuc.edu/msp/ or call<br />

(217) 333-8146.<br />

Neuroscience Program (NSP)<br />

<strong>The</strong> NSP currently has over 70 affiliated faculty from 12 departments,<br />

<strong>and</strong> 60 students, studying the brain from a broad range <strong>of</strong> perspectives.<br />

Information <strong>and</strong> application forms are available at http://www.<br />

life.uiuc.edu/neuroscience/admission/index.html.<br />

Biophysics <strong>and</strong> Computational <strong>Biology</strong><br />

<strong>The</strong> Center for Biophysics <strong>and</strong> Computational <strong>Biology</strong> is interdisciplinary,<br />

consisting <strong>of</strong> over 40 faculty members who have appointments<br />

in departments in biology <strong>and</strong> engineering. Information <strong>and</strong><br />

application forms are available at www.life.uiuc.edu/biophysics/<br />

program/admissions.html.<br />

Department <strong>of</strong> <strong>Molecular</strong> <strong>and</strong> Integrative Physiology<br />

(MIP)<br />

<strong>School</strong> <strong>of</strong> <strong>Molecular</strong> <strong>and</strong> <strong>Cellular</strong> <strong>Biology</strong><br />

University <strong>of</strong> Illinois at Urbana-Champaign<br />

524 Burrill Hall<br />

407 South Goodwin Avenue<br />

Urbana, Illinois 61801<br />

Phone (217) 333-1735<br />

Fax (217) 333-1133<br />

www.mcb.uiuc.edu/departments/mip<br />

Reproductive <strong>Biology</strong><br />

Breast Cancer<br />

Nuclear Hormone Receptors<br />

Steroid Hormone Mechanisms<br />

Neuroendocrine Signaling<br />

Gene Regulation<br />

Relaxin<br />

Cardiovascular Physiology<br />

Adrenergic Regulation<br />

Cardiac Ion Channels<br />

Signaling Complexes<br />

Nuclear Receptors<br />

Cholesterol/Bile Acids<br />

Parkinson’s Disease<br />

Neurophysiology<br />

Neural Networks<br />

Sensory Processing<br />

Synaptic Plasticity<br />

Lig<strong>and</strong>-gated Ion Channels<br />

Fragile-X Syndrome<br />

Infertility


<strong>The</strong> Department <strong>of</strong> <strong>Molecular</strong> <strong>and</strong> Integrative Physiology embraces excellence <strong>and</strong> discovery in a broad spectrum <strong>of</strong> disciplines.<br />

Faculty<br />

Thomas J. Anastasio Sensorimotor transformations in the nervous system<br />

Milan Bagchi <strong>Molecular</strong> pathways <strong>of</strong> steroid hormone action<br />

Janice M. Bahr Regulation <strong>of</strong> ovarian follicular development <strong>and</strong> estrogen<br />

action in the male reproductive tract<br />

Philip M. Best Calcium channels in the heart: structure, function, <strong>and</strong><br />

regulation<br />

Charles L. Cox Functional organization <strong>and</strong> neuromodulation <strong>of</strong> thalamocortical<br />

circuits, neuronal excitability, synaptic physiology <strong>and</strong> plasticity,<br />

epilepsy<br />

M. Joan Dawson Nuclear magnetic resonance spectroscopic (NMRS) studies<br />

<strong>of</strong> living systems<br />

Fred Delcomyn Physiology <strong>and</strong> simulation <strong>of</strong> insect behavior<br />

Arthur L. DeVriesRole <strong>of</strong> glycopeptide <strong>and</strong> peptide antifreezes in Inhibition<br />

<strong>of</strong> ice crystal growth <strong>and</strong> recrystallization<br />

Albert S. Feng Sensory processing, neural basis <strong>of</strong> sound pattern recognition<br />

<strong>and</strong> sound localization, hearing aid technology<br />

Julia M. George Synuclein proteins <strong>and</strong> neurodegenerative disease<br />

Rhanor Gillette Neural network <strong>and</strong> cellular mechanisms <strong>of</strong> decisionmaking<br />

in behavior<br />

Martha U. Gillette <strong>Cellular</strong> <strong>and</strong> molecular mechanisms in the brain’s circadian<br />

clock: stimulus-transcription coupling, molecular gating <strong>of</strong> signal<br />

transduction, neurochemical regulators <strong>of</strong> circadian rhythms <strong>and</strong> sleep<br />

William T. Greenough Brain plasticity in learning <strong>and</strong> memory; cellular<br />

signalling in brain plasticity; mechanisms <strong>of</strong> brain development; role <strong>of</strong><br />

experience in brain maturation<br />

Claudio Grosman <strong>Molecular</strong> mechanisms <strong>of</strong> neurotransmitter-gated ion<br />

channels<br />

Gary A. Iwamoto Neural control <strong>of</strong> the cardiorespiratory <strong>and</strong> locomotor<br />

apparatuses<br />

Eric Jakobsson Computational studies <strong>of</strong> biological membranes: the<br />

physical <strong>and</strong> chemical bases <strong>of</strong> life at the interface<br />

Benita Katzenellenbogen Regulation <strong>of</strong> gene expression, signal transduction,<br />

<strong>and</strong> cell proliferation by hormones <strong>and</strong> growth factors; mechanisms<br />

<strong>of</strong> hormone <strong>and</strong> antihormone action in normal <strong>and</strong> cancer cells; functional<br />

analyses <strong>of</strong> nuclear hormone receptors<br />

Byron Kemper Regulation <strong>of</strong> P450 gene expression; structural basis for cellular<br />

localization, membrane association, assembly, <strong>and</strong> substrate interaction<br />

<strong>of</strong> P450<br />

Jongsook Kim Kemper <strong>Molecular</strong> basis <strong>of</strong> the regulation <strong>of</strong> hepatic cholesterol<br />

<strong>and</strong> glucose metabolism: applications to metabolic disorders including<br />

hypercholesterolemia, diabetes, obesity<br />

Richard Kollmar <strong>Molecular</strong> basis <strong>of</strong> hearing <strong>and</strong> balance in the zebrafish<br />

Kurt E. Kwast <strong>Molecular</strong> mechanisms <strong>of</strong> oxygen sensing; oxygen-regulated<br />

gene expression; genomic remodeling <strong>of</strong> metabolism; yeast molecular<br />

genetics<br />

Esmail Meisami Brain development; hormones <strong>and</strong> growth factors in recovery<br />

from early neural retardation; neurobiology <strong>of</strong> the olfactory system<br />

Ann M. Nardulli Regulation <strong>of</strong> estrogen-responsive genes<br />

Mark E. Nelson Computational neuroscience, sensory coding, neural control<br />

<strong>of</strong> sensory acquisition, sensorimotor integration<br />

Lori T. Raetzman Notch signaling pathway in pituitary gl<strong>and</strong> development<br />

<strong>and</strong> disease<br />

Edward J. Roy Immunotherapy<br />

O. David Sherwood Hormonal regulation <strong>of</strong> birth <strong>and</strong> lactation in mammals:<br />

physiological <strong>and</strong> biochemical effects <strong>of</strong> relaxin on the cervix <strong>and</strong><br />

mammary gl<strong>and</strong>s<br />

Jonathan V. Sweedler Distribution <strong>and</strong> dynamic release <strong>of</strong> neurotransmittors<br />

<strong>and</strong> neuropeptides from individual neurons<br />

Colin A. Wraight Electron <strong>and</strong> proton transfer in proteins <strong>and</strong> across membranes;<br />

biological energy conversion; control <strong>of</strong> redox c<strong>of</strong>actor function;<br />

molecular engineering <strong>of</strong> lig<strong>and</strong>-protein interactions<br />

Kevin Y. Xiang GPCR signaling transduction, membrane signaling complexes<br />

<strong>of</strong> beta adrenergic receptors <strong>and</strong> their function in cardiac myocyte<br />

<strong>and</strong> neuron<br />

Resources<br />

Beckman Institute for Advanced Science <strong>and</strong> Technology<br />

Multidisciplinary research institute focusing on biological intelligence,<br />

human-computer intelligent interaction, <strong>and</strong> molecular nanostructures.<br />

Institute for Genomic <strong>Biology</strong><br />

Research themes involving key MCB faculty members. State-<strong>of</strong>-the-art<br />

micr<strong>of</strong>abrication lab, plant growth facility, <strong>and</strong> a microscopy suite.<br />

Roy J. Carver Biotechnology Center<br />

William Keck Center for Comparative <strong>and</strong> Functional Genomics: genetic<br />

organization, evolution, <strong>and</strong> function <strong>of</strong> genomes; sequencing <strong>and</strong> oligonucleotide<br />

synthesis; DNA microarray facilities; bioinformatics. Protein<br />

Sciences Facility: protein sequence analysis; peptide synthesis; 2D gel<br />

electophoresis. Immunological Resources Center: creation, purification,<br />

<strong>and</strong> immunochemical labeling <strong>of</strong> antibodies. Flow Cytometry Facility: a<br />

state-<strong>of</strong>-the art cell sorter, satellite flow cytometry machines. Transgenic<br />

Mouse Facility <strong>and</strong> Career Services Office.<br />

<strong>The</strong> National Center for Supercomputing Applications (NCSA)<br />

Interdisciplinary research center for computational science; complementing<br />

traditional methods <strong>of</strong> laboratory experimentation.

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