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Traditional Posters: Interventional - ismrm

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in performing more of these procedures, but workflow and procedure speed are significant hurdles for full adoption. Here, a<br />

navigation tool for guiding and tracking the needle in real-time under MRI is presented.<br />

1841. Navigated Liver Biopsies in a Closed-Bore MR Scanner: First Clinical Experience<br />

Michael Moche 1 , Gregor Thörmer 1 , Nikita Garnov 1 , Jochen Fuchs 1 , Susann Heinig 1 , Tim<br />

Riedel 1 , Thomas Kahn 1 , Harald Busse 1<br />

1 Leipzig University Hospital, Leipzig, Germany<br />

MRI has been shown to be of great clinical utility for the guidance of various procedures. In a closed-bore scanner, the simplest<br />

approach is to manipulate the instrument outside the bore and move the patient inside for control imaging only. Potential benefits for<br />

percutaneous biopsies in the liver have been investigated in 15 patients by using a flexible add-on navigation solution which even<br />

allowed interventions in obese patients. Real time navigation was provided by following the virtual instrument on properly<br />

reformatted images of a 3D roadmap. In combination with a specific breathhold protocol, punctures could be reliably performed in<br />

reasonable times.<br />

1842. Evaluation of a Real Time MR-Guided Interactive Navigation Device: Phantom and<br />

Animal Experiments<br />

Steffi Valdeig 1 , Barry Fetics 2 , Li Pan, 1,3 , Clifford R. Weiss 1 , Erez Nevo 2 , Dara L.<br />

Kraitchman 1 , Frank K. Wacker 1<br />

1 Department of Radiology and Radiological Science, Johns Hopkins University, Baltimore, MD, United States;<br />

2 Robin Medical Inc., Baltimore, MD, United States; 3 Center for Applied Medical Imaging, Siemens<br />

Corporation, Corporate Research, Baltimore, MD, United States<br />

Purpose: To test the feasibility and accuracy of a tool that allows for interactive adjustments of the needle plane during a MR guided<br />

puncture Method: Experiments were performed in vivo and in phantoms using a gradient based navigation system for real time MR<br />

guided punctures in a wide bore MR imager. To assess for accuracy of the system the distance of the needle tip (virtual and real) to the<br />

target was determined on MR control scans. Result: The mean 3D total error was 4.9 ±2.8mm in the phantom. The system error was<br />

less than 2 mm. In the animal, successful punctures of the target structures could be confirmed in all punctures. Conclusion: The<br />

combination of image overlay with real time adjustment of the virtual needle and real-time imaging feedback provides an accurate and<br />

intuitive means to perform percutaneous interventions in a wide bore MR imager.<br />

1843. Fast and Precise: Real Time MR-Guided Prostate Biopsy at 3 Tesla in Animal<br />

Experiment.<br />

Patrik Zamecnik 1 , Axel j. Krafft 2 , Florian Maier 3 , Jaane Rauschenberg 2 , Michael Bock 2<br />

1 DKFZ German Cancer Research Center), Heidelberg, Baden-Württemberg, Germany; 2 DKFZ (German Cancer<br />

Research Center); 3 DKFZ (German Cancer Resaerch Center)<br />

Real time MR-guided prostate biopsy at 3 Tesla in animal experiment proved to be a fast an precise method to perform prostate<br />

biopsies.<br />

1844. Development of a Pneumatic Robot for MRI-Guided Transperineal Prostate<br />

Intervention<br />

Sang Eun Song 1 , Nathan Bongjoon Cho 1 , Iulian Iordachita 2 , Gregory Scott Fischer 3 ,<br />

Junichi Tokuda 4 , Nobuhito Hata 4 , Gabor Fichtinger 5 , Clare Tempany 4<br />

1 Engineering Research Center, The Johns Hopkins University, Baltimore, MD, United States; 2 Department of<br />

Mechanical Engineering, The Johns Hopkins University, Baltimore, MD, United States; 3 Mechanical<br />

Engineering Department, Worcester Polytechnic Institute, Worchester, MA, United States; 4 Brigham and<br />

Women’s Hospital, Boston, MA, United States; 5 School of Computing,, Queen’s University, Kingston, Ontario,<br />

Canada<br />

As accurate needle positioning helps the prostate cancer detection and treatment, a number of MRI-compatible robots have been<br />

introduced. However, problems exist due to the strong magnetic field and limited workspace. Pneumatic actuator has the minimum<br />

distraction in the environment. However, it has poor controllability. To overcome the controllability problem, a simple external<br />

damping mechanism that can enhance accuracy was developed. Based on the actuator mechanism and workflow optimized modular<br />

design approaches, a new pneumatically actuated 4-DOF parallel robot for MRI-guided prostate intervention was developed. A<br />

preliminary evaluation was conducted with satisfying actuator average position error of 0.2mm.<br />

1845. Development and Preliminary Evaluation of a MRI-Guided Transrectal Prostate<br />

Intervention<br />

Axel Krieger 1,2 , Sang Eun Song 3 , Nathan Bongjoon Cho 3 , Peter Guion 4 , Iulian<br />

Iordachita 1 , Gabor Fichtinger 5 , Louis L. Whitcomb 1<br />

1 Department of Mechanical Engineering, The Johns Hopkins University, Baltimore, MD, United States;<br />

2 Sentinelle Medical Inc., Toronto, Canada; 3 Engineering Research Center, The Johns Hopkins University,<br />

Baltimore, MD, United States; 4 National Institute of Health, Bethesda, MD, United States; 5 School of<br />

Computing,, Queen’s University, Kingston, Ontario, Canada<br />

This paper reports the design, development and MRI compatibility evaluation of a transrectal prostate robot for MRI-guided<br />

intervention. The robot employs an automated needle guide with the goal of increasing needle placement accuracy and reducing<br />

interventional procedure times. The design of the robot, employing piezo-ceramic-motor actuated needle guide and manual needle<br />

insertion, is reported. Results of a MRI compatibility study show no reduction of MRI image SNR with the motors disabled and a 40%

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