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Is Survival the Only Thing that Matters?

Is Survival the Only Thing that Matters?

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Study Endpoints- <strong>Survival</strong><br />

• Overall survival<br />

• Disease-free survival (DFS): Ma<strong>the</strong>matical curve<br />

estimating <strong>the</strong> % of subjects <strong>that</strong> will survive and be<br />

disease free at various periods of time after initial<br />

treatment.<br />

– Patients must be disease free at some time during treatment for<br />

this to be valid<br />

• Progression-free survival (PFS): Ma<strong>the</strong>matical curve<br />

estimating <strong>the</strong> percentage of patients who will survive<br />

and be without evidence of disease progression at<br />

various time periods after initial treatment

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