Ticagrelor versus clopidogrel in patients with acute coronary ...
Ticagrelor versus clopidogrel in patients with acute coronary ...
Ticagrelor versus clopidogrel in patients with acute coronary ...
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Study medication at study entry<br />
CABG<br />
Medication<br />
Median treatment duration, days (range)<br />
Median delay from hospital admission, h<br />
<strong>Ticagrelor</strong><br />
(n=632)<br />
226 (26–364)<br />
9.0<br />
Clopidogrel<br />
(n=629)<br />
223 (28–353)<br />
6.8<br />
Total <strong>clopidogrel</strong> (OL + IP) pre-randomization to 24 h, %<br />
300 mg<br />
600 mg<br />
Open-label <strong>clopidogrel</strong> pre-randomization, %<br />
Any dose<br />
75 mg (50–150 mg)<br />
300 mg (151–449 mg)<br />
600 mg (≥450 mg)<br />
83.4<br />
16.6<br />
46.5<br />
14.9<br />
22.5<br />
9.2<br />
81.2<br />
18.8<br />
44.2<br />
10.5<br />
21.5<br />
12.2<br />
OL = open-label; IP = <strong>in</strong>vestigational product