01.04.2014 Views

Ticagrelor versus clopidogrel in patients with acute coronary ...

Ticagrelor versus clopidogrel in patients with acute coronary ...

Ticagrelor versus clopidogrel in patients with acute coronary ...

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

Study medication at study entry<br />

CABG<br />

Medication<br />

Median treatment duration, days (range)<br />

Median delay from hospital admission, h<br />

<strong>Ticagrelor</strong><br />

(n=632)<br />

226 (26–364)<br />

9.0<br />

Clopidogrel<br />

(n=629)<br />

223 (28–353)<br />

6.8<br />

Total <strong>clopidogrel</strong> (OL + IP) pre-randomization to 24 h, %<br />

300 mg<br />

600 mg<br />

Open-label <strong>clopidogrel</strong> pre-randomization, %<br />

Any dose<br />

75 mg (50–150 mg)<br />

300 mg (151–449 mg)<br />

600 mg (≥450 mg)<br />

83.4<br />

16.6<br />

46.5<br />

14.9<br />

22.5<br />

9.2<br />

81.2<br />

18.8<br />

44.2<br />

10.5<br />

21.5<br />

12.2<br />

OL = open-label; IP = <strong>in</strong>vestigational product

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!