08.04.2014 Views

presence of aflatoxins in smoked-dried fish sold in abeokuta, ogun ...

presence of aflatoxins in smoked-dried fish sold in abeokuta, ogun ...

presence of aflatoxins in smoked-dried fish sold in abeokuta, ogun ...

SHOW MORE
SHOW LESS

You also want an ePaper? Increase the reach of your titles

YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.

Increased liver cancer <strong>in</strong>cidence associated with aflatox<strong>in</strong> exposure occurs <strong>in</strong> areas where<br />

there is <strong>in</strong>take <strong>of</strong> high levels <strong>of</strong> <strong>aflatox<strong>in</strong>s</strong> (<strong>of</strong>ten higher than the regulatory limits).<br />

5.3 RECOMMENDATIONS<br />

There is a need for further study <strong>of</strong> <strong>in</strong>teraction between <strong>aflatox<strong>in</strong>s</strong> and hepatitis virus and<br />

jo<strong>in</strong>t effects <strong>of</strong> <strong>aflatox<strong>in</strong>s</strong> and hepatitis virus on liver cancer.<br />

Pharmacok<strong>in</strong>etic studies <strong>of</strong> <strong>in</strong>gested <strong>aflatox<strong>in</strong>s</strong> <strong>in</strong> humans (with and without liver<br />

disease).<br />

Populations with a low mean aflatox<strong>in</strong> <strong>in</strong>take are likely to achieve a decrease <strong>in</strong> liver<br />

cancer cases by <strong>in</strong>troduc<strong>in</strong>g lower aflatox<strong>in</strong> limits.<br />

Surveillance should be targeted to staple foods.<br />

HACCP (Hazard analysis and critical control po<strong>in</strong>t) pr<strong>in</strong>ciples can be used to highlight<br />

the roles that fungal ecology play <strong>in</strong> aflatox<strong>in</strong> contam<strong>in</strong>ation, prevention and control.<br />

The stakeholders <strong>in</strong> the production cha<strong>in</strong>, particularly farmers, <strong>fish</strong> processors should be<br />

made aware <strong>of</strong> the importance <strong>of</strong> measures to reduce aflatox<strong>in</strong> contam<strong>in</strong>ation.<br />

Tra<strong>in</strong><strong>in</strong>g programmes for the development <strong>of</strong> practical control and management strategies<br />

should be developed and conducted <strong>in</strong> order to set up strong aflatox<strong>in</strong> management<br />

programmes.<br />

Complicated aflatox<strong>in</strong> analysis procedure should be replaced with commercial kits such<br />

as Veratox Quantitative Aflatox<strong>in</strong> Test used for this particular work, which is easy to run.<br />

Health regulatory bodies such as NAFDAC should carry this out so that aflatox<strong>in</strong> can be<br />

easily detected and samples conta<strong>in</strong><strong>in</strong>g them <strong>in</strong> very high concentrations should be<br />

discarded.<br />

39

Hooray! Your file is uploaded and ready to be published.

Saved successfully!

Ooh no, something went wrong!