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“A structure based flexible search method for motifs in RNA” Isana ...

“A structure based flexible search method for motifs in RNA” Isana ...

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Our tree representation<br />

� Compressed as <strong>in</strong> [Shapiro, 1988] + a node <strong>for</strong><br />

every s<strong>in</strong>gle strand component <strong>in</strong> multiloops.<br />

� Includes additional <strong>in</strong><strong>for</strong>mation on nodes and<br />

on edges <strong>for</strong> the purpose of sequence analysis.<br />

� It is more <strong>in</strong><strong>for</strong>mative than Shapiro’s tree<br />

representation and more compact then Zhang’s.<br />

� This leads to a precise screen<strong>in</strong>g of the target<br />

text by first select<strong>in</strong>g candidates whose<br />

structural tree representation is similar to that of<br />

the query, and then further filter<strong>in</strong>g these<br />

candidates by apply<strong>in</strong>g sequence<br />

considerations.

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