“A structure based flexible search method for motifs in RNA” Isana ...
“A structure based flexible search method for motifs in RNA” Isana ...
“A structure based flexible search method for motifs in RNA” Isana ...
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The Algorithm - Motivation<br />
� Po<strong>in</strong>t-mutation events could easily result <strong>in</strong> an extra bulge <strong>in</strong> an RNA <strong>structure</strong>.<br />
� However, <strong>in</strong> some cases the functional homology to the orig<strong>in</strong>al, non-mutated<br />
<strong>structure</strong> is still preserved.<br />
� The suggested alignment should be <strong>flexible</strong> enough to allow the deletion of degree-<br />
2 nodes from the target tree.<br />
bulge<br />
riboswitch and its functional homologue
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