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“A structure based flexible search method for motifs in RNA” Isana ...

“A structure based flexible search method for motifs in RNA” Isana ...

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Pur<strong>in</strong>e Riboswitch<br />

� Riboswitches:<br />

� Part of an RNA molecule.<br />

� Directly b<strong>in</strong>d a small target molecules with high aff<strong>in</strong>ity and as<br />

a consequence they respond with con<strong>for</strong>mational switch<strong>in</strong>g that<br />

affects the gene’s activity.<br />

� Pur<strong>in</strong>e riboswitch - b<strong>in</strong>ds guan<strong>in</strong>e/aden<strong>in</strong>e to regulate<br />

pur<strong>in</strong>e metabolism and transport.

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