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Dual Organ Transplant – Double the Bliss - NUH

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<strong>NUH</strong> news bites<br />

Link between low birth weight and metabolic<br />

diseases<br />

<strong>NUH</strong> researchers are looking into <strong>the</strong> link between low<br />

birth weight and obesity by studying <strong>the</strong> metabolic profile<br />

of overweight adults.<br />

06<br />

The three-year study, which is part two of <strong>the</strong> Singapore Adult<br />

Metabolism Study (SAMS), is led by Dr Eric Khoo (Consultant,<br />

Division of Endocrinology). It is funded by <strong>the</strong> National Research<br />

Foundation and administered by <strong>the</strong> National Medical Research<br />

Council. The Principal Investigators include Associate Professor<br />

Tai E Shyong (Head and Senior Consultant, Division of<br />

Endocrinology) and Associate Professor Lee Yung Seng (Senior<br />

Consultant, Division of Paediatric Endocrinology and Diabetes).<br />

On top of studying participants from birth in a related study -<br />

Growing up in Singapore Towards healthy Outcomes (GUSTO),<br />

<strong>the</strong> researchers are working backwards by recruiting healthy<br />

Chinese men aged 21 to 40 with a BMI of 23 to 30, and looking<br />

into <strong>the</strong>ir medical histories including birth weight. The ultimate<br />

aim of SAMS is to design strategies to reduce <strong>the</strong> burden of<br />

chronic diseases like diabetes and obesity.<br />

Participants first undergo a battery of tests to measure <strong>the</strong>ir<br />

energy expenditure and physical activity levels, fat distribution<br />

A SAMS participant having his metabolic readings recorded as part of <strong>the</strong> study.<br />

and how sensitive <strong>the</strong>y are to insulin. They <strong>the</strong>n go through a<br />

four-month weight loss programme, followed by post-intervention<br />

studies and follow-up visits over a year at three-monthly intervals.<br />

While <strong>the</strong> target is for participants to lose five to eight per cent of<br />

<strong>the</strong>ir weight, one has managed to shed 10 per cent of his original<br />

weight since he joined <strong>the</strong> study.<br />

The study started in September 2010 and it has since recruited<br />

24 participants. The team hopes to recruit 180 participants<br />

eventually. Interested individuals may wish to contact Mr Melvin<br />

Tan via 9061 7588 or email info@devos-sams.sg.<br />

<strong>NUH</strong> doctors produce iPad application on<br />

minimally invasive surgery<br />

Surgeons at <strong>the</strong> <strong>NUH</strong> have become <strong>the</strong> first in Singapore to develop a medical application<br />

on iTunes, <strong>the</strong> Apple online store.<br />

The information in <strong>the</strong> application is based on <strong>the</strong> second edition of <strong>the</strong> Manual of Endo-<br />

Laparoscopic and Single-Port Surgery by Associate Professor Davide Lomanto, Director of<br />

<strong>NUH</strong>’s Minimally Invasive Surgical Centre and Dr Cheah Wei Keat, Chairman Medical Board<br />

at Jurong Health Services and Visiting Consultant with <strong>NUH</strong>’s Department of Surgery. The<br />

manual is used in teaching medical students in Singapore and more than a dozen surgeons<br />

from <strong>NUH</strong> had contributed chapters to <strong>the</strong> book.<br />

On <strong>the</strong> iPad, a subscriber gets not only all <strong>the</strong> text information but also videos showing how<br />

procedures are done. The application also has a section on <strong>the</strong> equipment needed and how<br />

each one works.<br />

This Application is an interactive teaching tool that is<br />

accessible any time, anywhere. Medical students and resident<br />

trainees in surgery can surf up <strong>the</strong> Manual and know about<br />

indications and contraindications for every surgical procedure, <strong>the</strong><br />

kind of preoperative work up <strong>the</strong> patient requires before surgery,<br />

to <strong>the</strong> type of instrumentation and follow-ups required.<br />

A/Prof Davide Lomanto, Director, Minimally Invasive Surgical Centre, <strong>NUH</strong>

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