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Annual Report 2002 - Roche

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Pharmaceuticals: Operating profit and EBITDA margins improved further<br />

Operating profit increased by 11% to 4.1 billion Swiss francs, representing 21.1% of sales in <strong>2002</strong><br />

after 19.5% in 2001. EBITDA totalled 6.0 billion Swiss francs, up by 7%, and the EBITDA margin<br />

increased from 29.7% to 31.0%. This strong result is driven by the prescription business while the<br />

OTC results weakened compared to the previous year.<br />

Total prescription sales increased by 10% in local currencies primarily driven by the strong<br />

performance of the oncology franchise and other key products such as CellCept and NeoRecormon,<br />

partly offset by the impact of generics on Roaccutane/Accutane. The consolidation of Chugai<br />

from 1 October <strong>2002</strong> contributed 4 percentage points to the growth of the prescription business.<br />

Marketing and distribution costs increased in line with sales. Increased costs for the launch of<br />

new products such as Pegasys and Fuzeon were partially offset by a more focused spend on<br />

growth areas resulting from the Pharmaceuticals Division restructuring. The research and development<br />

pipeline was complemented by a number of in-licensing deals, which increased R&D<br />

costs substantially due to upfront and milestone payments. The result also includes the gain on<br />

the disposal of Neupogen of 217 million Swiss francs.<br />

Due to the acquisition of Chugai and in order to improve comparability, the Japan prescription<br />

business is now reported separately. It consists of the Nippon <strong>Roche</strong> prescription business until<br />

30 September <strong>2002</strong> and Chugai from 1 October <strong>2002</strong>. Consequently the <strong>Roche</strong> prescription<br />

business as shown in this report excludes the business in Japan for both years. The profitability<br />

of the <strong>Roche</strong> prescription business was improved further and the operating profit margin is now<br />

at 25.0%. The Genentech prescription business achieved another very strong sales and profit<br />

growth. The EBITDA margin of 37.0% represents Genentech’s strong contribution to the Group’s<br />

operating cash generation. The <strong>2002</strong> operating profit of Genentech includes 603 million Swiss<br />

francs of amortisation mainly arising from the acquisition of Genentech by <strong>Roche</strong>. The Japan<br />

prescription business grew by 63% as a result of the acquisition of Chugai. The operating profit<br />

margin decreased to 14.4% due to the strength of the Swiss franc relative to the Japanese yen,<br />

higher launch costs for new products and the recurring acquisition accounting charges. On an<br />

annualised basis these acquisition accounting impacts amount to approximately 90 million Swiss<br />

francs.<br />

OTC sales fell by 2% in local currencies. The main factors were weak sales of Aleve and the economic<br />

difficulties in Latin America. Operating profit decreased by 14% to 244 million Swiss francs,<br />

primarily due to the decline in sales, start-up costs for a new production facility, the absence of<br />

second half 2001 gains on product disposals as part of the ongoing product portfolio streamlining<br />

and intensified marketing efforts for product roll-outs in the second half of <strong>2002</strong>. The operating<br />

profit margin was 15.7% compared to 17.2% in 2001.<br />

Diagnostics: another strong result<br />

The sales development again significantly outperformed the market with an overall growth rate<br />

of 11% in local currencies. Sales growth in the high margin business areas Molecular Diagnostics<br />

and Diabetes Care was particularly strong. Operating profit increased by 14% to 1,131 million<br />

Swiss francs and EBITDA by 8% to 1,984 million Swiss francs. Profitability again improved with the<br />

operating profit margin up by 1.2 percentage points to 15.6% and the EBITDA margin up by<br />

0.8 percentage points to 27.4%. Increased operating costs, in particular for research and development<br />

and licensing activities, were more than offset by the strong sales growth.<br />

Other<br />

The result of ‘Other’ consists of the costs of Corporate Headquarters. In <strong>2002</strong>, costs increased<br />

compared to 2001 mainly due to the launch of corporate initiatives.<br />

Financial Review 63

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