Download PDF - asian pharma press

More documents

Recommendations

Info

Asian J. Res. Pharm. Sci. 2013; Vol. 3: Issue 1, Pg 42-44 Palmitic acid [AJPSci.] Anti-inflammatory, Analgesic and Antipyretic activity Aqueous extract of Coccinia indica (leaves) produced marked analgesic and antipyretic activity at 300mg/kg dose when compared with standard drugs (Morphine and Paracetamol). The extract also showed significant antiinflammatory activity. 5 (Junaid Niazi et al ) Antimicrobial activity Petroleum ether and methanolic extract of Coccinia indica showed the highest antimicrobial activity against grampositive organisms. 6 Oleic Acid Antibacterial Activity Ethanol and aqueous extracts of Coccinia indica showed promising antibacterial activity against the Enterobacter aerogenes, Pseudomonas aeruginosa, Staphylococcus epidermidis, Bacillus subtilis and Salmonella typhimurium by agar well diffusion method and broth dilution method. 7 Linoleic Acid Antihyperglycemic activity Chronic administration of Coccinia Indica (fruits) extract at dose of 200mg/kg for 14 days reduces the blood glucose level of the diabetes induced animals as compared to diabetic control group. 8 Hepatoproetcective activity Coccinia indica leave extract at dose 400 mg/kg body weight showed potent hepatoproetcective activity in albino rats. 9 Riboflavin TRADITIONAL USES: The fruit of Coccinia indica is useful in biliousness and diseases of blood. The green fruit is chewed to cure sores on the tongue. The bark of root is used as cathartic. The leaves are applied externally in eruptions of the skin. The leaves of this plant are boiled in gingelly oil and applied externally in ringworm, psoriasis and itch. The leaves are also used as expectorant and antispasmodic. The oil is used in application to ulcers and as an injection into chronic sinuses. The plant is also used in the treatment of gonorrhea. Taraxerol PHARMACOLOGICAL PROFILE: Anthelmintic Activity Methanol extract of Coccinia indica fruits in the concentration of 50 mg/ml showed potent anthelmintic activity against Pheretima posthuma. 3 Antioxidant activity Oral administration of ethanolic extract of Coccinia indica (leaf) extract (CLEt) (200 mg/kg body weight) for 45 days resulted in a significant reduction in thiobarbituric acid reactive substances and hydroperoxides in rats. 4 Table 1 Vernacular names of Coccinia indica S.N. Names Language 1 Kanduri Hindi 2 Bimbu Bengal 3 Galedu Gujerati 4 Bimbi Marathi 5 Kundru Punjab 6 Bimbaka Sanskrit 7 Kovai Tamil 8 Kundaru Urdu Table 2 Scientific Classification Kingdom Plantae Division Magnoliophyta Class Magnoliophyta Order Cucurbitales Family Cucurbitaceae Genus Coccinia Species Indica 43
Asian J. Res. Pharm. Sci. 2013; Vol. 3: Issue 1, Pg 42-44 [AJPSci.] CONCLUSION: Now a day’s major concern of researchers is focused on the development of new novel herbal drugs that could be useful in the treatment of various disease problems. This versatile medicinal plant is the distinctive source of various types of chemical compounds, which are accountable of the various activities of the plant. Hence, extensive exploration is required to utilize their therapeutic efficacy to combat diseases. ACKNOWLEDGEMENT: Yogesh Shivhare, the author, thankfully acknowledges to Mr. Rakesh Punekar, Head and Vice-Principal, RKDF College of Pharmacy, Bhopal (M.P.), in preparation of this manuscript. REFERENCE: 1. www.ayushveda.com 2. Kirtikar KR, Basu BD. Indian Medicinal Plant. 1976: Vol. II, M/s Bishwas Singh, Nirali prakasan, Dehradun, 1151-1154. 3. Shivhare Yogesh, Soni Prashant, Singh Priya, Dangi Sonal and Baghel S Sourabh. Evaluation of Anthelmintic Activity of Coccinia indica (fruits). J. Chem. Pharm. Res., 2011: 3(1); 488- 491 4. Venkateswaran S and Pari L.. Effect of Coccinia indica leaves on antioxidant status in streptozotocin-induced diabetic rats. Journal of ethano<strong>pharma</strong>cology. 2003: vol 84, issue 2, 163-168. 5. Niazi Junaid, Singh Parabhdeep and Bansal Yogita. Antiinflammatory, Analgesic and Antipyretic activity of aqueous extract of fresh leaves of Coccinia indica. Inflammo<strong>pharma</strong>cology. 2009: 17: 239-244. 6. Syed Zeenat Shaheen, Bolla Krishna, Kandukuri vasu and Singara Charya MA. Antimicrobial activity of the fruit extracts of Coccinia indica. African Journal of Biotechnology. 2009: Vol. 8 (24); 7073-7076. 7. Hussain Arshad, Wahab Shadma, Zarin Iffat and Sarfaraj Hussain MD. Antibacterial Activity of the Leaves of Coccinia indica (W. and A) Wof India. Advances in Biological Research. 2010: 4 (5): 241-248. 8. Gunjan Manish, Jana K Goutam, Jha AK and Mishra Umashanker. Pharmacognsotic and Antihyperglycemic study of Coccinia indica. International Journal of Phytomedicine. 2010: 2; 36-40. 9. Kumar B. Shyam, D. Gnanasekaran V, Jaishree KP and Channabasavaraj. Hepatoprotective activity of Coccinia indica leaves extract. Int J Pharm Biomed Res 2010, 1(4), 154-156. 44
Page 1: Asian J. Res. Pharm. Sci. 2013; Vol

Download PDF - asian pharma press

Create successful ePaper yourself

Delete template?

Save as template?