Resume - Rajshahi University

CURRICULUM VITAE
MD. AKTAR UZZAMAN CHOUDURI, Ph. D
Associate Professor, Department of Pharmacy, University of Rajshahi
Rajshahi 6205, Bangladesh
Cell Phone: +88 01712 792350
of
Email: auchow5@yahoo.com
CAREER OBJECTIVE
To build up career in research sector where my academic knowledge, innovation, past research
expertise can be utilized to provide new information for science.
To improve career in teaching sector for the optimum delivery to the students.
To involve in a team of biological research that will try to play an important role in modern science.
PERSONAL PROFILE
Name
: Md. Aktar Uzzaman Chouduri
Father’s name : Md. Azim Uddin Chouduri
Mother’s name : Khodeza Khanom
Date of Birth : 04 December 1975
Nationality : Bangladesh
Place of Birth : Rajshahi City, Bangladesh
Religion
: Islam
Marital Status : Married (one child)
Blood group : B +ve
Sex
: Male
Occupation : University Teacher
Academic affiliation : Associate Professor
Mailing Address : Department of Pharmacy, University of Rajshahi,
Rajshahi-6205, Bangladesh.
Telephone : Office +88-0721-750041, Ext 4110
Mobile +88-01712-792350
Fax / Email : +88-0721-750064, auchow5@yahoo.com
Home Address : Vill.- Mohabbatpur, P.O.- Chanderara, P.S.- Bagmara,
Dist- Rajshahi 6250, Bangladesh.
ACADEMIC QUALIFICATIONS
Ph. D, 2008:
Completed 4 years research work leading to Ph. D on the activation and inactivation mechanism of
macromolecular enzyme 20S proteasome and its enzymatic and proteomic analysis from the
Department of Biology, Faculty of Science, Shizuoka University, Japan.
Grade Secured
Course studied
Thesis title
: A (Excellent), 80-89 marks
: Environmental Science Research-I, Environmental Science Research-II,
Environmental Science Research-III, Exercise in Environmental Science, Advanced
Environmental Science-I, Advanced Functional Physiology, Advanced Molecular
and Cellular Biology
: Functional and biochemical study of 20S proteasome in yeast temperature-sensitive
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Technique
used
Supervisor
Co-Supervisor
Study medium:
mutant, rpt6-1 and Xenopus oocytes.
: Various column chromatographic technique for protein purification, in vitro
proteasome activity assay, enzyme kinetics of 20S proteasome, SDS-PAGE,
native-PAGE, overlay proteasome activity assay, Western blotting, in-vitro peptide
hydrolyzing activity assay of proteasome, 2D-gel electrophoresis, protein sequencing
by MALDI-TOF mass spectrometry, PCR
: Professor Dr. Shinpei Yamada, Department of Biology, Faculty of Science,
Shizuoka University, Japan. Email: sbsyama@ipc.shizuoka.ac.jp
: Dr. Toshinobu Tokumoto (sbttoku@ipc.shizuoka.ac.jp),
Professor Dr. Kiyoshi Yamauchi (sbkyama@ipc.ac.jp),
Professor Dr. Masahito Yamazaki (spmyama@ipc.shizuoka.ac.jp)
: English
M. Pharm., 1996:
Completed 2 years M. Pharm. (Master of Pharmacy) course, 1 yr theory and 1 yr research, from the
Department of Pharmacy, Faculty of Science, University of Rajshahi, Bangladesh.
Class / Division
Course studied
Thesis Title
Technique
used
Supervisor
Study Medium
: Secured first class (3 rd position) with 63.66% marks.
: Advanced pharmaceutical analysis; Medicinal Chemistry, Pharmacology &
Toxicology; Advanced Pharmaceutical Technology & Toxicology; Advanced
Pharmaceutical Technology, Cosmetology & Pharmaceutics.
: Studies on Actinomyces species and its metabolites.
: Cell culture by serial dilution technique, Solvent extraction technique, Thin layer
chromatography (TLC), antagonistic activity measurement by disk diffusion assay
method, subacute toxicity study, Histopathological study.
: Professor Dr. Md. Abdul Gafur, Department of Pharmacy, Faculty of Science,
University of Rajshahi, Bangladesh. Email: gafurraj1@yahoo.com
: English
B. Pharm., 1995:
Completed 3 years B. Pharm. (Bachelor of Pharmacy) course from the Department of Pharmacy,
Faculty of Science, University of Rajshahi, Bangladesh.
Class / Division
Course studied
Study Medium
: Secured first class (4 th position) with 62.25% marks.
: Inorganic Chemistry, Organic Chemistry, Physical Chemistry,
Pharmacognosy, Physiology & Biochemistry, Pharmaceutical Microbiology,
Statistics, Pharmacology, Pharmaceutics, Pharmaceutical Analysis & Quality
Control, Medicinal Chemistry, Industrial & Hospital Pharmacy,
Pharmacokinetics & Biopharmaceutics.
: English
H.S.C., 1992:
Completed 2 years Higher Secondary Certificate (HSC) examination from Rajshahi Govt. College,
Rajshahi, Bangladesh.
Class / Division
Course studied
Study Medium
: Secured first division with 70.6% marks.
: Bengali (Language & Literature), English (Language & Literature), Physics,
Chemistry, Biology (Plant & Animal Biology), Mathematics
: Bengali (Mother language).
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S. S. C., 1990:
Completed 10 years Secondary School Certificate (SSC) examination from Rajapur Secondary
School, Borhaigram, Natore, Bangladesh.
Class / Division
Course studied
Study Medium
: Secured first division with 73.5% marks.
: Bengali (Language & Literature), English (Language & Literature), General
Science (Physics & Chemistry), Biological Science (Botany & Zoology),
General Mathematics, Higher Mathematics, Geography, Religious
Education, Social Science.
: Bengali (Mother Language).
RESERCH EXPERIENCES
Ph. D:
Completed four years research work leading to Ph. D on Biochemistry entitled “Functional and
biochemical study of 20S proteasome in yeast temperature-sensitive mutant, rpt6-1 and Xenopus
oocytes” and published two research articles in reputed international peer reviewed journal in
fulfillment of the requirement for Ph. D degree.
M. Pharm.:
Completed two years research work on Microbiology entitled “Studies on Actinomyces species and
its metabolites” and submitted a thesis paper to the department of Pharmacy, University of Rajshahi,
Bangladesh in partial fulfillment of the requirement for M. Pharm. degree.
WORK DONE DURING RESEARCH PERIOD
Ph. D:
Cell culture and growth phenotypic study of yeast mutant, rpt6-1.
Purification of 20S proteasome from yeast, Xenopus, and several animal tissues.
SDS-, fatty acid-, pH-, Zn 2+ -concentration dependent proteolytic activity measurement of 20S
proteasome from various sources.
Subunit compositional analysis of 20S proteasome by 1- and 2-dimensional electrophoresis, Western
blotting.
Identification of all subunits of 20S proteasome by MALDI-TOF MS.
Investigation of proteolytic activity of 20S proteasome by shift of cell culture from permissive
temperature to restrictive temperature.
Complementation study of yeast mutant.
Proposition of proteasome channel in rpt6-1 yeast mutant.
M. Pharm.:
Isolation and Characterization of antagonistic Streptomyces species.
Selection of the suitable medium for optimum growth of the organism.
Selection of appropriate culture conditions for optimum production of the antimicrobial compounds.
Production of antimicrobial compounds in suitable liquid broth medium.
Optimization of physicochemical conditions for the production of antimicrobial compounds.
Characterization of antimicrobial compounds isolated from Streptomyces species.
In vitro antimicrobial activities of the isolated compounds.
Toxicological studies on rats and brine shrimp of the isolated compounds.
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ACHIEVEMENT OF RESEARCH
Ph. D:
Very low level of proteasome activity was found in rpt6-1 yeast mutant.
Subunit composition pattern of 20S proteasome in rpt6-1 mutant was different to that of wild-type
counterpart.
Two subunits of proteasome in rpt6-1, α1 & α7, showed slow mobility and different isoelectric
focusing in 2-DE compared to that of wild type.
The changes on α1, α7 were not a consequence of phosphorylation.
The changes on α1, α7 were disappeared when culture temperature had been shifted to restrictive
temperature.
A precursor form of α1, α7 regulate the proteasome channel in absence of Rpt6 ATPase.
M. Pharm.:
Two antimicrobial compounds were isolated. One of which is di- (2-ethyl hexyl) phalate and another
one had not been identified due to its poor amount.
All the compounds showed moderate to strong antimicrobial activities.
Biochemical parameters were normal on subacute toxicity studies on rats with the isolated
compounds.
TRAINING OBTAINED
An in-plant training of the period of six weeks duration had been taken in “Beximco Pharmaceutical
Company Ltd” an ISO certified leading pharmaceutical company in Bangladesh. During the training
period dispensing, manufacturing, packaging, in process quality control operation of various
pharmaceutical products of different dosage forms were observed and carried out in practice.
A cGMP and Validation training had been taken in “Opsonin Chemical Industries Ltd
(Pharmaceutical Branch)” another ISO certified leading pharmaceutical company in Bangladesh.
EMPLOYMENT HISTORY
‣ Production Officer : Nov 2000 – Jul 2001 Opsonin Chemical Industries Ltd., Bangladesh.
‣ Production Executive : Jul 2001 – Aug 2001 Square Pharmaceutical Company Ltd.,
Bangladesh.
‣ Lecturer : Sep 2001 – Sep 2004 Department of Pharmacy, University of Rajshahi,
Bangladesh.
‣ Assistant Professor : Sep 2004 – May 2009 Department of Pharmacy, University of Rajshahi,
Bangladesh.
‣ Associate Professor : May 2009 – to date Department of Pharmacy, University of Rajshahi,
Bangladesh.
TEACHING GIVEN ON COURSES DURING LAST 2 YEARS
• Under-graduate course: Physical Pharmacy, Quality Control-Quality Assurance & Validation,
Microbiology, Pharmaceutical Technology, Physiology & Biochemistry.
• Post-graduate Courses: Advanced Pharmaceutical Analysis, Advanced Biopharmaceutics.
MEMBERSHIP OF PROFESSIONAL BODIES
1. Registered Pharmacist of Pharmacy Council of Bangladesh.
2. Member of Pharmacy Graduate Association
3. Member of Rajshahi University Teacher’s Association
4. Member of a local Science Club
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OTHER EXPERIENCES
Computer Skill: Well conversant with popular packages like Microsoft Word, Microsoft Excel, Power
Point.
LANGUAGE PROFICIENCY
1. Bengali : Reading, Writing, and Speaking
2. English : Reading, Writing, and Speaking
3. Japanese : Speaking
AWARDS
1. Japanese Govt. Scholarship (Monbukagakusho 2004) for higher study (Ph. D) in Japan.
2. University Scholarship for excellent result in B. Pharm. and M. Pharm. examination.
3. Bangladesh Govt. Stipend for excellent result in primary, secondary and higher secondary
education.
REFERENCES
1. Md. Ekramul Haque, Ph. D
Professor
Department of Pharmacy
Otish Diponkar University, Dhaka, Bangladesh
♦ Phone: +88-0721-750133 (Home), +88-01711-952286 (Mobile)
♦ Fax: +88-0721-750064
♦ Email: mdekramul@yahoo.com
2. Md. Anwar Ul Islam, Ph. D
Professor
Department of Pharmacy
University of Rajshahi, Rajshahi-6205, Bangladesh
♦ Phone: +88-0721-750071 (Home), +88-01716-325611 (Mobile)
♦ Fax: +88-0721-750064
♦ Email: profanwarulislam@yahoo.com
3. Maruf Ahmed, Ph. D
Professor and Chairman
Department of Pharmacy
University of Rajshahi, Rajshahi-6205, Bangladesh.
♦ Phone: +88-01718-442311 (Mobile)
♦ Fax: +88-0721-750064
♦ Email: amaruf2000@yahoo.com
♦ Homepage: http://www.ru.ac.bd/phar/maruf_ahmed.htm
4. Toshinobu Tokumoto, Ph. D
Associate Professor
Department of Biology, Faculty of Science
Shizuoka University, Japan 422-8529
♦ Phone: +81-54-238-4778
♦ Fax: +81-54-238-4778
♦ Email: sbttoku@ipc.shizuoka.ac.jp
♦ Home page: www.ipc.shizuoka.ac.jp/~sbttoku/
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LIST OF PUBLICATIONS
1. Chouduri, A. U., Tokumoto, T., Dohra, H., Ushimaru, T., and Yamada, S., Functional and
biochemical characterization of the 20S proteasome in a yeast temperature-sensitive mutant, rpt6-
1, BMC Biochem., 9, 20, Jul., 2008.
1. Chouduri, A. U., Mishina, K., Shimizu, T., Yamazaki, M., Tokumoto, T., and Yamada, S., High
affinity Zn 2+ inhibitory site(s) for the trypsin-like peptidase of the 20S proteasome, Arch. Biochem.
Biophys., 477, 113-120, Sep., 2008.
3. Chouduri, A. U., Rahman, M. A. A., and Gafur, M. A., In vitro antibacterial and cytotoxic
activities of a brown antibiotic metabolite from a strain of Actinomycetes, The Sciences, 1, 206-
208, Aug., 2001.
4. Rahman, M. A. A., Gafur, M. A., Islam, M. E., Anwar-Ul-Islam, M., and Chouduri, A. U., Subacute
toxicity studies of a metabolite of Streptomyces species, Pak. J. Biol. Sci., 5, 1067-1069,
Oct., 2002.
5. Sultan, M. Z., Sathi, Z. S., Biswas, M. H. U., Chouduri, A. U., Rahman, M. A. A., and Gafur, M.
A., In vitro toxicological studies of metabolites of Streptomyces species on brine shrimp, J. Med.
Sci., 2, 240-242, Sep., 2002.
6. Barman, R. K., Sathi, Z. S., Habib, M. A., Chouduri, A. U., Biswas, M. H. U., Gafur, M. A., and
Rahman, M. A. A., Toxicity study of 8-Propionato-2-β (D+) Glucosyl-9, 10-Pyranopyridine
isolated from Streptomyces species on long Evan’s rats, Biotechnology, 1, 94-99, Jul., 2002.
7. Sultan, M. Z., Khatune, N. A., Sathi, Z. S., Bhuiyan, M. S. A., Sadik, M. G., Chouduri, A. U.,
Gafur, M. A., and Rahman, M. A. A., In vitro antibacterial activity of an active metabolite isolated
from Streptomyces species, Biotechnology, 1, 100-106, Jul., 2002.
8. Sultan, M. Z., Sathi, Z. S., Bhuiyan, M. S. A., Chouduri, A. U., Biswas, M. H. U., Gafur, M. A.,
and Rahman, M. A. A., Sub-acute toxicity studies of a metabolite of Streptomyces species,
Biotechnology, 1, 88-93, Jul., 2002.
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