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Global Tuberculosis Report -- 2012.pdf

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FIGURE 2.12 Trends in estimated TB mortality rates 1990–2011 and forecast TB mortality rates 2012–2015, by WHO<br />

region. Estimated TB mortality excludes TB deaths among HIV-positive people. Shaded areas represent uncertainty<br />

bands. a The horizontal dashed lines represent the Stop TB Partnership target of a 50% reduction in the mortality rate by<br />

2015 compared with 1990. The other dashed lines show projections up to 2015.<br />

60<br />

40<br />

Africa<br />

8<br />

6<br />

The Americas<br />

60<br />

50<br />

40<br />

Eastern Mediterranean<br />

4<br />

30<br />

Rate per 100 000 population per year<br />

20<br />

0<br />

8<br />

Europe<br />

2<br />

0<br />

60<br />

South-East Asia<br />

20<br />

10<br />

0<br />

25<br />

20<br />

Western Pacific<br />

6<br />

40<br />

15<br />

4<br />

2<br />

20<br />

10<br />

5<br />

0<br />

0<br />

1990 1995 2000 2005 2010 2015 1990 1995 2000 2005 2010 2015 1990 1995 2000 2005 2010 2015<br />

0<br />

a<br />

The width of an uncertainty band narrows as the proportion of regional mortality estimated using vital registration data increases or the quality and completeness of the<br />

vital registration data improves.<br />

2.5 Strengthening measurement of the<br />

burden of disease caused by TB: the<br />

WHO <strong>Global</strong> Task Force on TB Impact<br />

Measurement<br />

The estimates of TB incidence, prevalence and mortality<br />

and their trend presented in sections 2.1–2.4 are based on<br />

the best available data and analytical methods. In 2009,<br />

methods were fully revised, and since April 2009 consultations<br />

have been held with 96 countries accounting for<br />

89% of the world’s TB cases. Nonetheless, there is considerable<br />

scope for further improvement. This final section<br />

of the chapter describes the latest status of efforts to<br />

improve measurement of the burden of disease caused by<br />

TB, under the umbrella of the WHO <strong>Global</strong> Task Force on<br />

TB Impact Measurement.<br />

Established in mid-2006, the mandate of the WHO<br />

<strong>Global</strong> Task Force on TB Impact Measurement is to ensure<br />

the best possible assessment of whether the 2015 global<br />

targets for reductions in the burden of disease caused by<br />

TB are achieved, to report on progress in the years leading<br />

up to 2015 and to strengthen capacity for monitoring and<br />

evaluation at the country level. The Task Force includes<br />

representatives from leading technical and financial partners<br />

and countries with a high burden of TB. 1<br />

At its second meeting in December 2007, the Task<br />

Force defined three strategic areas of work: 2<br />

● strengthening surveillance towards the ultimate goal<br />

of direct measurement of incidence and mortality from<br />

notification and VR systems;<br />

● conducting surveys of the prevalence of TB disease in<br />

a set of global focus countries that met epidemiological<br />

and other relevant criteria; and<br />

● periodic revision of the methods used to translate surveillance<br />

and survey data into estimates of TB incidence,<br />

prevalence and mortality.<br />

The third area of work is discussed in more detail in<br />

Annex 1. The following sections focus on the first two<br />

strategic areas of work. Full details of the Task Force’s<br />

work are available on its web site. 3<br />

1<br />

Partners that are actively participating in the work of the Task<br />

Force include the Centers for Disease Control and Prevention<br />

in the USA, the European Centre for Disease Prevention and<br />

Control, the <strong>Global</strong> Fund, the Health Protection Agency in the<br />

UK, the KNCV <strong>Tuberculosis</strong> Foundation, the London School<br />

of Hygiene and Tropical Medicine in the UK, the Research<br />

Institute for <strong>Tuberculosis</strong> in Japan, the Union and USAID.<br />

Many countries with a high burden of TB are engaged in the<br />

work of the Task Force.<br />

2<br />

TB impact measurement: policy and recommendations for how to<br />

assess the epidemiological burden of TB and the impact of TB control.<br />

Geneva, World Health Organization, 2009 (Stop TB policy<br />

paper no. 2; WHO/HTM/TB/2009.416).<br />

3<br />

www.who.int/tb/advisory_bodies/impact_<br />

measurement_taskforce<br />

GLOBAL TUBERCULOSIS REPORT 2012 21

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