Overview of ankylosing spondylitis genetics and pathogenesis
Overview of ankylosing spondylitis genetics and pathogenesis
Overview of ankylosing spondylitis genetics and pathogenesis
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Possible role <strong>of</strong> ERAP1 (endoplasmic<br />
reticulum aminopeptidase 1) in AS?<br />
• Trimming <strong>of</strong> “arthritogenic” peptides<br />
• Effect on B27 folding in ER<br />
• Effect on stability <strong>of</strong> B27 on cell surface