Emerging cytokines and cytokine signalling molecules as ...
Emerging cytokines and cytokine signalling molecules as ...
Emerging cytokines and cytokine signalling molecules as ...
You also want an ePaper? Increase the reach of your titles
YUMPU automatically turns print PDFs into web optimized ePapers that Google loves.
Anti-<strong>cytokine</strong> therapies developed for psori<strong>as</strong>is<br />
CT637<br />
HMGB1-RAGE interaction<br />
Generic name<br />
Cytokine Target<br />
Etanercept, Infliximab, Adalimumab TNF<br />
Ustekinumab<br />
Briakinumab<br />
------<br />
Secukinumab<br />
Brodalumab<br />
Ixekizumab<br />
CNTO1959<br />
SCH900222<br />
Fezakinumab (ILV-094)<br />
NN8226<br />
IL12/23 p40<br />
IL12/23 p40 (withdrawn)<br />
IL-17<br />
IL-17<br />
IL-17<br />
IL-23p19<br />
IL-23p19<br />
IL-22<br />
IL-20<br />
AMG 714<br />
IL-15<br />
ABX-IL8 IL-8 (modest results in ph<strong>as</strong>e 2,<br />
MEDI 545<br />
discontinued for psori<strong>as</strong>is)<br />
IFNalpha (ph<strong>as</strong>e 1 completed, no<br />
clinical activity in established dise<strong>as</strong>e)