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MRA acquisition

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Contrast-enhanced <strong>MRA</strong> at 3T<br />

Signal ratio: contrast-enhanced arterial blood – fat tissue<br />

T 1<br />

arterial blood<br />

T 1<br />

fat<br />

R 1<br />

Magnevist<br />

T 1<br />

blood + Gad (5 mmol/L)<br />

Signal ratio blood/fat<br />

TR=3.5 ms, a = 30°, C blood<br />

= 5 mmol/L<br />

1.5 T<br />

1250 ms<br />

343 ms<br />

4.1 L/mmol/s<br />

47 ms<br />

5.15<br />

3.0 T<br />

1650 ms<br />

382 ms<br />

3.7 L/mmol/s<br />

52 ms<br />

5.30<br />

High-resolution <strong>MRA</strong> @ 3 Tesla<br />

1.5T <strong>MRA</strong><br />

3.0T <strong>MRA</strong><br />

TR / TE [ms]<br />

3.77 / 1.39<br />

3.14 / 1.1<br />

Flip angle [°]<br />

25<br />

23<br />

Bandwidth [Hz/Px] ∆: 1.5T 3.0T350<br />

510<br />

Matrix<br />

512 x 80%<br />

Voxel volume -28%<br />

512 x 80%<br />

FOV [mm²]<br />

400 x 87%<br />

400 x 81%<br />

Slab thickness +8%<br />

Phase Oversampling [%]<br />

0<br />

8<br />

Voxel size [mm³] Scan time 0.8 -6%<br />

0.65<br />

Spatial resolution [mm³]<br />

1 x 0.8 x 1<br />

0.9 x 0.8 x 0.9<br />

Better background (fat) suppression for <strong>MRA</strong><br />

Higher vessel contrast!<br />

Decrease contrast amount by 10%-20%<br />

Scan time [s]<br />

19<br />

Partitions<br />

80<br />

Parallel imaging<br />

GRAPPA factor 3<br />

Michaely HJ, Nael K et al. Rofo. 2005; 177: 800-804<br />

18<br />

96<br />

GRAPPA factor 3<br />

From spatial to temporal resolution<br />

1.5T<br />

3.0T<br />

Spatial resolution 1.4 x 1.4 x 1.5 mm, 10 ml CM<br />

3.7 s (PAT3) Temporal Resolution 2.9 s (PAT4)<br />

3T<br />

Michaely HJ, et al. Radiology 2007; 244: 907-913<br />

Kramer H, et al.<br />

Invest Radiol 2007; 42: 477-483<br />

From spatial to temporal resolution<br />

(2D-)PAT and image geometry<br />

TWIST at 3 Tesla<br />

Courtesy of Mike Notohamiprodjo MD and Christian Glaser MD, LMU Munich

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