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Department of Higher education, Govt. of M.P.<br />

Semester wise Syllabus for Postgraduates<br />

As recommended by Central board of Studies and<br />

Approved by HE the Governor of M.P.<br />

Session : 08-09<br />

M.Sc. Previous Zoology<br />

II Sem<br />

IV Paper<br />

Topic . Molecular Cell Biology and genetics<br />

Unit . I<br />

- Biomembrane<br />

- Molecular composition arrangement and functional consequences<br />

- Transport across cell membrane diffusion active transport, pumps, uniports, symports<br />

and antiports<br />

- Micro filaments and microtubules structure and dynamics<br />

-Cell movements intracellular transport, role of kinesin and dynein<br />

Unit . II<br />

-Cell . Cell signaling<br />

- Signaling from plasma membrane to nucleus : types of signals(G protein and protein kinases),target<br />

cells and effector organs.<br />

- Cell surface receptors of signaling molecule<br />

- Second messenger system<br />

Unit . III<br />

- Cell . Cell adhesion and communication<br />

- Ca++ dependent homophilic cell . cell adhesion -cadherin<br />

- Ca++ independent homophilic cell . Substratum adhesion - integrin<br />

- Ca++ independent homophilic cell . cell adhesion –Immunoglobulin gene family molecules<br />

- Gap junctions and connexins<br />

- Genome organization, hierarchy in organization<br />

-Chromosomal organization of genes and non-coding DNA<br />

Unit .IV Sex determination<br />

- Sex determination in drosophila<br />

- Sex determination in mammals<br />

- Basic concept of dosage compensation<br />

- Cytogenetics of human chromosomes<br />

- Elementary idea of Human genome project (HGP)<br />

Unit . V<br />

- General idea of Genetic Diseases<br />

- Human gene therapy<br />

- Prenatal diagnosis & genetic counseling<br />

- Genetic screening

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