WIBObarrier® OCS - Open Containment Systems WIBObarrier ...

WIBOjekt® and WIBObarrier® Air Curtain Systems.
The perfect protection for person, product and environment.
Filling • Weighing • Sampling • Research
Safe handling
with high potent products / API
WIBObarrier® OCS - Open Containment Systems
WIBObarrier® CCS - Closed Containment Systems

WIBObarrier® - Duo
Open Containment Systems
WIBObarrier® - Duo
as a seated workplace for four workers, used in a
microbiological laboratory.
Ventilation technology
H14
Air guidance principle
WIBObarrier®- Duo
WIBObarrier®- Duo
The Barrier fulfils the requirements of exposure
limit and protection of person according to DIN EN
12469,C3 with both sides free front opening 300
mm high and a product protection/clean room
class ISO 5 according to EN ISO 14644-1 within
the working area.
WIBObarrier® - Duo
A safe workplace for sampling packages containing
high potent steroid agents and/or APIs (active
pharmaceutical ingredients).
Integrated in a pallet conveying system which passes
through the Barrier. The sampling is carried out from
two sides to ensure that the person does not have to
bend over the packages during sampling.
Priority is given to the protection of person with a
maximum product exposure of OEL 1-10 µg/m 3
and the product protection/clean-room quality ISO 7
according to EN ISO 14644-1 above the product.

WIBObarrier® - Horizontal
Open Containment Systems
The reliable air guidance system for
modern filling technology.
The system consists of two modules, a transmitter and a
receiver,which are positioned vertically opposite each
other. The filling and emptying station for packages, big
bags, containers and so forth are located between them.
H14 filtered air flows through the transmitter laminator
horizontally over the filling/emptying station towards
the receiver unit. The air curtain which builds up
through the vertical and horizontal transmitter unit
ejectors supports and stabilises this clean air curtain.
In addition, a stable clean-airflow is drawn in by the
receiver unit and is built up through the filling/
emptying station ensuring that the emissions emanating
from the filling/emptying station are contained within
the protected area and are safely conveyed to the extraction
unit. At the same time penetration of emissions emanating
from personnel or from the room into the product
area are prevented.
Cross contaminations which could result from there being
a number of filling/emptying stations with different products
in one room, are prevented by the high directional
stability of the airflow.
Flow technology settings enable prioritisation of
personnel or product protection.
WIBObarrier Horizontal
Abluft
exhaust air
Zuluft
supply air
Barrier
Stabilisator
stabilizer
Air guidance principle
WIBObarrier®- Horizontal
Advantages
■ Protection factor > 100,000, possible for
both personnel and product protection
■ Product exposure for personnel and room
according to OEL 10-30 µg/m 3 achievable
■ Air quality up to ISO 7 according to EN ISO
14644-1 when set up in the" black" area
■ No product removal as a result of low air speeds
with high directional stability
■ Free access from three sides makes integration
of filling/emptying equipment and materials
handling possible
■ Modular construction means configuration as
either stationary or mobile units is possible
■ Also available in an acid resistant plastic version
WIBObarrier ® - Horizontal

VARIO-Isolator with WIBOjekt®
Absolute protection of personnel by the isolator when handling high riskpotent materials.
Effective protection of personnel by WIBOjekt® when handling high potent materials.
The VARIO-Isolator is used where a controlled atmosphere
isolated from the surrounding area affording protection
of person and product at the same time needs to
be created.
The VARIO-Isolator is operated at 70 Pa below atmospheric
pressure. The unit operates with supply and exhaust air
system. Exhaust is 100 %.
The purity class corresponds to Class 5 according to
EN ISO 14644-1.
The Hepa exhaust filter is installed as a "pousse-pousse"
filter system (contamination free changeable) in the system
area.
The work surface is also the base of the isolator. Equipping
the work area is carried out through the alpha beta
double cover lock flanged onto the left hand side.
A waste chute with a sliding lockable lid and continuous
bag is located on the right hand side.
The isolator stands on a resistant floor unit including
integrated extraction. The floor unit is equipped with a
removable tub where a 20 liter tank is located to catch
cleaning fluid. An overfill safety device is inserted in the
tank so that when the adjustable filling level is reached it
sets off an alarm.
Weiss GWE GmbH
Wiechmannsallee 3
27798 Hude
Germany
Tel.: +49 (0) 4484 189-0
Fax: +49 (0) 4484 189-189
contact@gwe.de
www.gwe.de
The WIBOjekt air guidance system is used for
work at an open front panel. In this case an
ejector track is fitted in the front and the exhaust
volume flow is increased from 30 to 300 m 3 /h.
The contaminated air from the work area is pulled
along by the ejector system which creates a cleanair
curtain around the work area and is led to the
extraction opening which is fitted below the
exhaust air filters.
The clean-air curtain remains stable even if the
operator reaches through it. This robust retention
keeps contaminant escape within the levels set
according to the German Chemicals Law (BG
Chemie).
WIBObarrier / WIBOjekt = Registered trademark ®
Subject to technical alterations / Version: 01/2007

WIBObarrier®- CCS
as weighing and dispensing table for API
■ Infinitely adjustable sliding front panel
with glove ports
■ Material air locks on both sides for
removal and target package
■ Lift and tilt table for removal packages
■ Integrated label printer
2 WIBObarrier®- CCS
installed in sequence
■ Open reach through in the Barrier
work areas
■ Infinitely adjustable front panels with
glove ports
■ Integrated media connections
WIBObarrier®- combined with
WIBOjekt®- table
as laboratory workplace for high potent API
WIBObarrier®- CCS
■ Double leaf front door with horizontally
sliding safety glass front panel
■ Drum location station over the whole width
■ Integrated media connections
■ Transfer hatch to the second WIBObarrier®
WIBObarrier®- CCS
■ Table top over the whole width with integrated
waste chute
■ Top hinged front panel with glove ports
WIBOjekt®- table
■ Drum station
■ Double leaf front door in safety glass with
glove ports
■ Transfer hatch to the second WIBObarrier®
CCS – Configurations
WIBObarrier®- CCS
as weighing and dispensing table for API
■ Front door with glove ports
■ Drum station
Cleaning lock
■ Transfer hatch with pneumatic
shutter to the Barrier
■ Compressed air for cleaning inliners
■ Inliner welding gun
■ Front door with glove ports
Loading lock
■ Front door with glove ports
■ Conveyor for dispatch packages at
ground level, equipped with lifting
table
■ Table top with opening for dispatch
inliner
Transfer trolley between Barrier
and locks

WIBObarrier® - CCS
Closed Containment Systems
OCS - CCS - RABS - Isolators
Whats behind these concepts?
In developing the WIBObarrier® CCS - Closed
Containment Systems and WIBObarrier® OCS -
Open Containment Systems, Weiss has placed
priority on maintaining OEL-Level and clean-air quality
according to DIN EN ISO 14644-1, while retaining a
high degree of free access, flexibility and ergonomics.
The WIBObarrier®- system works according to the
three zone principle. The integrated jets in the front
hood area build up a stable clean-air curtain with
ejector effect (Barrier curtain) between the product and
operator/room.
Particles which escape in the product area are attracted
by the Barrier curtain like by a magnet and conveyed
directly to the contaminant extraction apertures, so
that staff and room are protected from product
emissions.
H14 filtered clean air is fed through the laminator in
the hood area into the work area with unidirectional
flow at a flow rate of 0.17 m/s to 0.45 m/s, adjustable
according to product and task, so that a clean
room zone is created.
Equipment and advantages
of the WIBObarrier® - CCS
■ Handling substances of
risk category (up to OEB 5)
as CCS-System with closed
front panel
■ Safe splash and carryover
protection through top
hinged front panel with
glove ports
■ Product/material transfer
through integrated locks or
direct through top hinged
front panel
■ Robust retention (Product
exposure) through the
stable Barrier curtain even
if the front panel is open
and there is free access
Particles which are liberated as a result of the operator
reaching into the work area, are also caught by the
Barrier curtain which conveys them back to the front
extractor, so that they do not contaminate the product.
WIBObarrier® - CCS, the Closed Containment
System among the WIBObarrier®-applications:
A multifunctional and flexible workplace for dispensing,
weighing and other handling of high potent pharmaceutical
substances and API (active pharmaceutical
ingredients).
The WIBObarrier® - CCS with closed front panel as
physical barrier between operator/room and product
area can be seen in sub areas as the first stage in a
series of contained safe workplaces, in the same way
as isolators and RABS systems.
F 9
Filter
H 13
OEB* OEL*
5 0 – 1 µg/m 3
4 1 – 10 µg/m 3
3 10 – 100 µg/m 3
2 100 – 1000 µg/m 3
1 1000 – 5000 µg/m 3
*OEB = Occupational Exposure Band
Danger category of a substance taking
*OEL = Occupational Exposure Limit
Average product exposure in breathin
measured in µg/m3,over 8 hours in a

Laminator for unidirectional airflow
Air guidance principle
WIBObarrier®- CCS / OCS
WIBO®-system solution
BDK-Isolator
WIBObarrier®-CCS
WIBObarrier®-CCS
WIBObarrier®-OCS
WIBObarrier®-Horizontal
WIBObarrier®-OCS
WIBObarrier®-Horizontal
WIBObarrier®-OCS
WIBObarrier®-Horizontal
WIBOjekt®
WIBObarrier®-OCS
WIBObarrier®-Horizontal
WIBOjekt®
toxicity into account
g area of operator,
40 hour, five day week.
Light
WIBObarrier® - OCS
Open Containment Systems
Equipment and advantages
of the WIBObarrier - CCS
■ Handling substances of risk
category (up to OEB 4)
■ Splash and carryover protection
through horizontally sliding
protection glass pane
for the protection of person,
equipped with glove ports
■ Unrestricted transfer of product
and material directly
through the front opening
■ Reaching through protection
for risk areas (Crusher /
mills) by means of controllable
light grids
■ Robust retention (Product
exposure) through the stable
Barrier curtain despite free
access, even without front
panel
When handling less dangerous substances the front
panel is clipped open or swung up and the Barrier
can be freely accessed and used as OCS.
WIBObarrier® - OCS, the Open Containment
System among the WIBObarrier®-applications:
An ergonomic workplace for the protection of operator,
room and product with integrated clean-room
zone up to ISO 5, for dispensing and filling, refining
and sampling.
Its patented air guidance system guarantees a robust
retention, despite the very gentle airflow, following
EN 14175-3, with free open front up to 1,000 mm
high. Splash and carryover protection can be provided by
installing a front panel, easy to be slid horizontally, available
even with glove ports.
Isolators, which guarantee the highest safety level
as far as personnel and product protection are concerned
are not always economically appropriate or necessary
because of the limited access in the product area
and the legal air and cleaning regulations at the
increasing flexibility requirements for production
processes.
Advanced development of the CCS/RABS (Restricted
Access Barrier Systems) means that the requirements
of increasing production flexibility in contained workplaces
have already been taken into account. RABS
are used primarily in aseptic filling.
In contrast to the isolator, RABS systems achieve only
a partial separation between sterile operations and
work area. This is possible without sacrificing quality
and safety limitations, because the operator is always
working in a clean room Class ISO 7 and ISO 5 is provided
in the product area of the RABS. In contrast to
isolators, RABS need not be operated in controlled
pressure areas and do not need to be hermetically
sealed.
WIBObarrier® - CCS is also available in RABS configuration.

WIBObarrier®- OCS
as weighing station for API
■ Horizontally sliding front panel
with glove ports
■ Table surface with weighing plate
■ Drum station
■ Lifting column, 200 kg capacity
■ Material lock with active cleaning
■ Transfer trolley from production
room up to lifting column
WIBObarrier®- OCS
as sampling station
■ Lift turntable for pallets
■ Transverse carriage for lift turntable
■ Pneumatic lift gates
■ Integrated pallet transport
OCS – Configurations
WIBObarrier®- OCS
as dispensing and laboratory workplace
■ Drum station
■ Lift and tilt column with drum turning
device 120 kg capacity
■ Weighing plate in the table surface
■ Spot extraction for container interiors
■ Catch tub with perforated plate cover
WIBObarrier®- OCS
as weighing station for API
■ Horizontally sliding front panel
with glove ports
■ Drum location station with floor
weighing machine
■ Articulated arm with weighing
terminal
WIBObarrier®- OCS
as dispensing station for API
■ Lift and tilt column with floor
weighing machine,150 kg capacity
■ Drum turning device
■ Drum location station for target
package with floor weighing
machine