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Intravitreal corticosteroid MWS 2012 Han.ppt (Read-Only)

Intravitreal corticosteroid MWS 2012 Han.ppt (Read-Only)

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12/12/11<br />

1 month after 6 Lucentis<br />

injections, VA 20/125<br />

7/12/11 OCT OD<br />

37<br />

<strong>Intravitreal</strong> <strong>corticosteroid</strong><br />

therapy<br />

Ø IOP and cataract are downsides<br />

Ø Probably second line to ranibizumab<br />

for DME and RVO<br />

Ø A viable option for DME in<br />

pseudophakes: less frequent<br />

injections, IOP control easier with<br />

some modalities vs. others<br />

Ø Sustained release devices show<br />

promise 38<br />

RVO and ranibizumab: CRUISE<br />

and BRAVO studies<br />

(references)<br />

Ranibizumab for macular edema following branch retinal vein occlusion: six-month primary<br />

end point results of a phase III study.<br />

Campochiaro PA.,et al.Ophthalmology. 117(6):1102-1112, 2010.<br />

Ranibizumab for macular edema following central retinal vein occlusion: six-month primary<br />

end point results of a phase III study.<br />

Brown DM, et al. Ophthalmology. 117(6):1124-1133.e1, 2010.<br />

39<br />

40<br />

10

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