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FINAL PROGRAM - Society for Immunotherapy of Cancer

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Program Schedule<br />

FRIDAY, NOVEMBER 4, 2011<br />

11:45 am - 12:00 pm Reversal <strong>of</strong> Local Immune Evasion Mechanisms and Regression <strong>of</strong> Human Merkel Cell Carcinoma by<br />

Intralesional Injection <strong>of</strong> Interferon-Beta<br />

Kelly G. Paulson<br />

University <strong>of</strong> Washington<br />

12:00 pm - 1:30 pm Lunch with Exhibits / Poster Viewing and Presentations<br />

(Box lunches provided to registered attendees.)<br />

12:30 pm - 1:30 pm Odd Numbered Poster Presentations by Authors<br />

1:30 pm - 3:00 pm Concurrent Session I: Immunology <strong>of</strong> <strong>Cancer</strong> Stem Cells and Epithelialto-Mesenchymal<br />

Transition (EMT)<br />

Chairs:<br />

Malcolm A.S. Moore, DPhil<br />

Memorial Sloan-Kettering <strong>Cancer</strong> Center<br />

Jeffrey Schlom, PhD<br />

National <strong>Cancer</strong> Institute, NIH<br />

1:30 pm - 2:00 pm <strong>Cancer</strong> Testis (CT) Antigens Expressed in Ovarian Tumor-Initiating Cells<br />

Malcolm A.S. Moore, DPhil<br />

Memorial Sloan-Kettering <strong>Cancer</strong> Center<br />

2:00 pm - 2:30 pm Immunotherapeutic Approaches to EMT and <strong>Cancer</strong> Stem Cells<br />

Claudia M. Palena, PhD<br />

National <strong>Cancer</strong> Institute, NIH<br />

Grand Ballroom Salons A-D<br />

Grand Ballroom Salon E<br />

2:30 pm - 2:45 pm Immunological Targeting <strong>of</strong> Epithelial to Mesenchymal Transition as a Strategy to Prevent Breast <strong>Cancer</strong><br />

Metastases<br />

Sandra Demaria, MD<br />

New York University School <strong>of</strong> Medicine<br />

2:45 pm - 3:00 pm Potential <strong>for</strong> Immunotherapeutic Control <strong>of</strong> CSC-like Cells Through their Expression <strong>of</strong> FAS and DR5 Death<br />

Receptors<br />

Trina Stewart, PhD<br />

Peter MacCallum <strong>Cancer</strong> Centre<br />

1:30 pm - 3:00 pm Concurrent Session II: Uncoupling Negative Regulation in the Tumor<br />

Microenvironment<br />

Chairs:<br />

Lieping Chen, MD, PhD<br />

Yale <strong>Cancer</strong> Center, Yale School <strong>of</strong> Medicine, Immunobiology<br />

Hassane M. Zarour, MD<br />

University <strong>of</strong> Pittsburgh<br />

1:30 pm - 2:00 pm Immune Checkpoints in the <strong>Cancer</strong> Microenvironment<br />

Lieping Chen, MD, PhD<br />

Yale <strong>Cancer</strong> Center, Yale School <strong>of</strong> Medicine, Immunobiology<br />

Grand Ballroom Salons G-H<br />

2:00 pm - 2:15 pm IL-12 Triggers an Inflammatory Gene Signature that Reverses Dysfunctional Antigen-presentation by<br />

Myeloid-Derived Cells Residing within Tumors<br />

Sid Kerkar, MD<br />

National <strong>Cancer</strong> Institute, Center <strong>for</strong> <strong>Cancer</strong> Research, NIH<br />

2:15 pm - 2:30 pm Acute Myeloid Leukemia Promotes Immune Evasion through Induction <strong>of</strong> Antigen-Specific T Cell Deletion<br />

Justin P. Kline, MD<br />

University <strong>of</strong> Chicago<br />

2:30 pm - 3:00 pm Targeting Multiple Inhibitory Pathways to Reverse Melanoma-induced T Cell Dysfunction<br />

Hassane M. Zarour, MD<br />

University <strong>of</strong> Pittsburgh<br />

3:00 pm - 3:15 pm Break<br />

18<br />

<strong>FINAL</strong> <strong>PROGRAM</strong> • SITC 26 TH ANNUAL MEETING<br />

November 4-6, 2011 • North Bethesda, MD • www.sitcancer.org

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