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FINAL PROGRAM - Society for Immunotherapy of Cancer

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Poster Listings<br />

99<br />

ANTI-TUMOR ROLE OF INTERFERON-GAMMA<br />

PRODUCING CD1D-RESTRICTED NKT CELLS IN<br />

MURINE MALIGNANT PLEURAL MESOTHELIOMA<br />

Tetsuzo Tagawa, Licun Wu, Zhihong Yun, Katrina Rey- Mcintyre, Marc<br />

de Perrot<br />

Latner Thoracic Surgery Research Laboratories, Toronto General<br />

Research Institute, University <strong>of</strong> Toronto, Toronto, ON, Canada<br />

100<br />

ELEVATED SERUM SOLUBLE CD40 LIGAND<br />

IN CANCER PATIENTS MAY PLAY AN<br />

IMMUNOSUPPRESSIVE ROLE<br />

Tara Talaie 1 , Catherine Jamis 1 , Austin Anderson 1 , Alessandra<br />

Jales 1 , Caroline Jochems 1 , Chiara Intrivici 1 , Kwong Y. Tsang 1 , Ravi<br />

A. Madan 1,2 , James W. Hodge 1 , James L. Gulley 1 , Jeffrey Schlom 1 ,<br />

Jianping Huang 1<br />

1<br />

Laboratory <strong>of</strong> Tumor Immunology and Biology, Center <strong>for</strong> <strong>Cancer</strong><br />

Research, National <strong>Cancer</strong> Institute, National Institutes <strong>of</strong> Health,<br />

Bethesda, MD<br />

2<br />

Medical Oncology Branch, Center <strong>for</strong> <strong>Cancer</strong> Research, National<br />

<strong>Cancer</strong> Institute, National Institutes <strong>of</strong> Health, Bethesda, MD<br />

101<br />

INTERVENTION OF MULTIPLE REGULATORY<br />

RECEPTORS INHIBITS Bim-MEDIATED T CELL<br />

DELETION AND PROMOTES DURABLE ADOPTIVE<br />

IMMUNOTHERAPY FOR CANCER<br />

Melissa M. Berrien 1 , Stephanie R. Jackson 1 , Jennifer M. Meyer 1 , Craig<br />

J. Rouskey 1 , Long M. Nguyen 1 , Hideo Yagita 2 , Philip D. Greenberg 3 ,<br />

Richard J. DiPaolo 1 , Ryan M. Teague 1<br />

1<br />

Molecular Microbiology and Immunology, Saint Louis University School<br />

<strong>of</strong> Medicine, St. Louis, MO<br />

2<br />

Immunology, Juntendo University School <strong>of</strong> Medicine, Tokyo, Japan<br />

3<br />

Immunology, University <strong>of</strong> Washington, Seattle, WA<br />

102<br />

COMBINING IMMUNETHERAPY AND<br />

CHEMOTHERAPY AGAINST CANCER: ADRIAMYCIN<br />

SENSITIZES HUMANTUMORSTO NK AND T CELL<br />

MEDIATED KILLING VIA AUGMENTED TRAIL<br />

SIGNALING<br />

Erik Wennerberg, Dhifaf Sarhan, Andreas Lundqvist<br />

Oncology-Pathology, Karolinska Institutet, Stockholm, Sweden<br />

103<br />

PROCLAIMSM: A PROSPECTIVE OBSERVATIONAL<br />

REGISTRY OF INTERLEUKIN-2 IN CANCER<br />

Michael Wong 3 , Howard Kaufman 1 , Michael Morse 2 , David<br />

McDermott 4 , Douglas Rizzo 5 , Yan Wu 6 , James Lowder 6<br />

1<br />

Rush University Medical Center, Chicago, IL<br />

2<br />

Duke University <strong>Cancer</strong> Center, Durham, NC<br />

3<br />

University <strong>of</strong> Southern Cali<strong>for</strong>nia Norris <strong>Cancer</strong> Hospital, Los Angeles,<br />

CA<br />

4<br />

Beth Israel Deaconess Medical Center, Boston, MA<br />

5<br />

CIBMTR Medical College <strong>of</strong> Wisconsin, Milwaukee, WI<br />

6<br />

Prometheus Laboratories Inc, San Diego, CA<br />

104<br />

DOSE ESCALATION OF ADJUVANT CAP1-6D/<br />

MONTANIDE/GM-CSF VACCINATION IN HIGH<br />

RISK PANCREATIC CANCER: INDUCTION OF CEA-<br />

SPECIFIC CD8+ T CELL RESPONSES AND EARLY<br />

SUGGESTION OF CLINICAL BENEFIT<br />

Yuanyuan Zha 1 , Thomas F. Gajewski 1,2 , Hedy Kindler 2<br />

1<br />

Human Immunologic Monitoring Facility, University <strong>of</strong> Chicago,<br />

Chicago, IL<br />

2<br />

Section <strong>of</strong> Hematology and Oncology, University <strong>of</strong> Chicago Medical<br />

Center, Chicago, IL<br />

INNATE IMMUNITY IN CANCER<br />

105<br />

ROLE OF NK AND NKT CELLS IN BREAST CANCER<br />

PATIENTS: ASSOCIATION WITH FAVORABLE<br />

PROGNOSIS<br />

Maria Libera Ascierto 1,4 , Kyle K. Payne 2 , Maciej Kmieciak 2 , Michael O.<br />

Idowu 3 , Catherine Dumur 3 , Davide Bedognetti 1 , Andrea De Maria 4 ,<br />

Ena Wang 1 , Francesco M. Marincola 1 , Masoud H. Manjili 2<br />

1<br />

Infectious Disease and Immunogenetics Section (IDIS), Department<br />

<strong>of</strong> Transfusion Medicine and Center <strong>for</strong> Human Immunology, National<br />

Institutes <strong>of</strong> Health, Bethesda, MD<br />

2<br />

Department <strong>of</strong> Microbiology & Immunology, Virginia Commonwealth<br />

University Massey <strong>Cancer</strong> Center, Richmond, VA<br />

3<br />

Department <strong>of</strong> Pathology, Virginia Commonwealth University Massey<br />

<strong>Cancer</strong> Center, Richmond, VA<br />

4<br />

Istituto G. Gaslini, Genova, Italy<br />

106<br />

GENOTYPIC, PHENOTYPIC AND FUNCTIONAL<br />

ANALYSIS OF MELANOMA<br />

Valeria De Giorgi 1 , Quizhen Lui 1 , Zoltan Pos 2 , John Wunderlich 3 ,<br />

Tara L. Spivey 1 , Lorenzo Uccellini 1 , Maria Libera Ascierto 1 , Davide<br />

Bedognetti 1 , Ena Wang 1 , Francesco M. Marincola 1<br />

1<br />

Department <strong>of</strong> Transfusion Medicine, National Institutes <strong>of</strong> Health,<br />

Bethesda, MD<br />

2<br />

Department <strong>of</strong> Genetics, Cell- and Immunobiology, Semmelweis<br />

University, Budapest, Hungary<br />

3<br />

Surgery Branch, NCI, National Institutes <strong>of</strong> Health, Bethesda, MD<br />

68<br />

<strong>FINAL</strong> <strong>PROGRAM</strong> • SITC 26 TH ANNUAL MEETING<br />

November 4-6, 2011 • North Bethesda, MD • www.sitcancer.org

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