CARDIAC CATH LAB - Mount Sinai Hospital

Top Ten Key Clinical Trials:
Study Study Sponsor PI Target Current
Title Details Enrollment & Status/
Study Sites Enrollment
FREEDOM Trial Randomized trial comparing National Heart, S. Sharma 2,058 (global) Ongoing/60
CABG vs. PCI in diabetic with Lung and subjects
multi-vessel disease. To evaluate Blood Institute enrolled.
whether PCI with DES is more (NHLBI) 28PCI/
or less effective than the
32CABG
existing standard of care CABG.
Multicenter, two-arm, open-label
prospective randomized
superiority trial with equal
allocation of three yrs duration.
IMPELLA A prospective,multi-center ABIOMED S. Sharma 650 (USA) Ongoing/
PROTECT II Trial randomized controlled trial of
18 subjects
the IMPELLA® RECOVER® LP 2.5
enrolled
System versus intra-aortic balloon
pump (IABP) in patients undergoing
nonemergent high-risk PCI.
SPIRIT Trial Prospective, two-arm, open-label, Abbott Vascular S. Sharma 500 Ongoing/
multicenter registry using Xience (global)/ 5 subjects
Prime EECSS and Xience Prime LL 10 Mount Sinai enrolled
EECSS in de novo native coronary
artery long lesions (length = 32 mm)
with reference vessel diameters
(2.25 mm to = 4.25 mm).
ABCD-PCI Trial Early ambulation and discharge St. Jude Medical M. Kim 600/6 sites (USA) Ongoing/
vs. overnight hospital stay for MSSM 222 subjects
patients undergoing successful
enrolled
vascular closure after PCI.
VWF Study To determine if BAV and AVR is MSSM J. Bander 100/Single Ongoing/
effective at reversing the acquired Center MSSM 15 subjects
Type 2- vWF syndrome seen in
enrolled
severe AS. Deficient vWF and
Factor-VIII complex is responsible
for bleeding.
36 Mount Sinai Hospital Cardiac Cath Lab