IDH - siesonline
IDH - siesonline
IDH - siesonline
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Different mutations have the same effect<br />
<strong>IDH</strong> muta5ons<br />
R 132 (<strong>IDH</strong>1)<br />
R 140 (<strong>IDH</strong>2)<br />
R 172 (<strong>IDH</strong>2)<br />
<strong>IDH</strong> muta5ons’<br />
frequency in 78<br />
AML samples<br />
7.7%<br />
9%<br />
4.4% 15.4%<br />
Ward et al, Cancer Cell 17, 225–234, March 16, 2010