The changing epidemiology of invasive aspergillosis
The changing epidemiology of invasive aspergillosis
The changing epidemiology of invasive aspergillosis
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Incidence <strong>of</strong> IA in immunocompromised children<br />
Underlying disease N Incidence IA (%)<br />
Malignancy<br />
solid tumour<br />
leukaemia<br />
ALL and AML<br />
99 177 0.5<br />
0.1<br />
1<br />
0.6 and 3.7<br />
Hematologic disorder (AA) 12 829 1.4<br />
Immunodeficiency<br />
WAS<br />
CGD<br />
CID<br />
cong. hypogammaglobulinaemia<br />
BMT<br />
allogeneic<br />
autologous<br />
Solid-organ transplant<br />
lung<br />
heart<br />
liver<br />
3733<br />
267<br />
322<br />
411<br />
119<br />
3013<br />
2219<br />
822<br />
1593<br />
39<br />
278<br />
569<br />
Zaoutis et al. Pediatrics 2006; 117: e711-e716<br />
3.2<br />
30<br />
6.5<br />
1.7<br />
3.3<br />
3.4<br />
4.5<br />
0.3<br />
0.3<br />
5<br />
0.3<br />
0.5
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