The changing epidemiology of invasive aspergillosis
The changing epidemiology of invasive aspergillosis
The changing epidemiology of invasive aspergillosis
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Parameter<br />
All<br />
(n=1<br />
27)<br />
Proven<br />
(n=56)<br />
Probable<br />
(n=49)<br />
Possible<br />
(n=2)<br />
Colonization<br />
(n=20)<br />
Age, yrs, mean 61 59 63 61 64<br />
Sex, male, n 84 39 35 2 8<br />
Haematological patients, n 38 26 12 0 0<br />
Nonhematological patients, n 89 30 37 2 20<br />
COPD, n 35 12 21 2 0<br />
Solid organ<br />
9 4 5 0 0<br />
transplants, n<br />
Systemic disease, n 17 6 8 0 3<br />
Cirrhosis, n 6 3 0 0 3<br />
Other, n 22 5 3 0 14<br />
SAPS II, mean 54 57 52 43 54<br />
Predicted mortality, % 53% 58% 49% 31% 51%<br />
Observed mortality, % 86% 98% 90% 0% 50%<br />
ICU length <strong>of</strong> stay, days 20 14 23 6.9% 32<strong>of</strong> all admissions 28<br />
Hemodialysis in ICU, n 54 27 20 0 Retrospective 7<br />
Mechanical ventilation, n 123 56 47 A lot 2 <strong>of</strong> autopsy 18data<br />
Neutropenia (
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