Radiation Exposure Effects in Humans - Department of Energy ...
Radiation Exposure Effects in Humans - Department of Energy ...
Radiation Exposure Effects in Humans - Department of Energy ...
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Estimat<strong>in</strong>g Hereditary Risks<br />
• Doubl<strong>in</strong>g Dose Method<br />
– Dose required to double spontaneous mutations<br />
– Estimated to be 1 Gy for low dose rate exposure <strong>in</strong><br />
humans (based on mice data)<br />
• Direct Method (<strong>in</strong>cidence <strong>of</strong> disorders observed<br />
<strong>in</strong> the first generation)<br />
• No statistically significant <strong>in</strong>dicators <strong>of</strong><br />
hereditary effects have been observed <strong>in</strong> the<br />
progeny <strong>of</strong> atomic-bomb survivors<br />
18
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