Neurobiology of Somatization
Neurobiology of Somatization
Neurobiology of Somatization
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Theoretical Mechanisms: Neurobiologic<br />
• Variable CNS modulation <strong>of</strong><br />
incoming sensory information, e.g.,<br />
– conversion = excessive inhibition<br />
– somatization = inadequate inhibition.<br />
• Melzack R & Wall P. Pain mechanisms: A new theory.<br />
Science. 1965;150:971-979<br />
• Wall P. The gate control theory <strong>of</strong> pain mechanisms: a reexamination<br />
and re-statement. Brain. 1978;101:1-18.