Neurobiology of Somatization
Neurobiology of Somatization
Neurobiology of Somatization
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Evidence for overlap<br />
•Opioids reduce social pain<br />
–1978 pr<strong>of</strong>oundly reduced crying<br />
and motor agitation <strong>of</strong> puppy dogs<br />
subjected to social isolation<br />
–1988 same in rhesus monkeys<br />
•neuro-endocrine also blocked<br />
•naloxone blocked both<br />
– implicating the opioid receptor
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