Neurobiology of Somatization

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Theoretical Mechanisms: A new Biopsychosocial Model A developmental theory •<strong>Somatization</strong> is not a disorder, but a developmentally appropriate response to stress in infants which normally diminishes with age as more mature capacities for distress and affect regulation are developed. • Landa A, Psychosom Med 2012;74:717
Theoretical Mechanisms: Biopsychosocial (Landa) • Negative early inter-personal experiences with caregivers may interact with genetic predisposition, leading to disrupted neural circuits involved in affect regulation and interpersonal functioning, • yielding the persistence into adulthood <strong>of</strong> developmentally earlier tendencies to experience distress somatically.
Page 1 and 2: Neurobiology of Somatization in < 2
Page 3 and 4: QUIZ: Who had more pain? A A B
Page 5 and 6: “By golly, you ARE crying on the
Page 7 and 8: DSM V Somatic Symptom Disorder •
Page 9 and 10: DSM V Illness Anxiety Disorder •
Page 11 and 12: Suffering in somatoform illness •
Page 13 and 14: Harrison’s Textbook 1962 (4th Edi
Page 15 and 16: Central Control Attention, emotion,
Page 17: PFC Cingulate & insula Somatosensor
Page 21 and 22: Theoretical mechanisms Why rejectio
Page 23 and 24: Evidence for overlap •Surgical ci
Page 25 and 26: Evidence for pain modulation • Ri
Page 27 and 28: Patient Centered Care, a pilot RCT
Page 29 and 30: QUIZ: Who had more pain? A A B
Page 31 and 32: The abstract ends here! Questions?
Page 33: Proc Natl Acad Sci U S A. 2003;100:

Neurobiology of Somatization

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