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EPR Spectroscopy

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EFFECT OF DIETHYLMALEATE<br />

(DEM) ON TUMOR REDOX STATUS<br />

4<br />

Tumor<br />

GSH (µg/mg tissue)<br />

2.5<br />

2.0<br />

1.5<br />

1.0<br />

0.5<br />

0.0<br />

GSH in Tumor<br />

Tissue<br />

Tumor<br />

(N=5)<br />

Tumor+DEM<br />

(N=8)<br />

Frequency<br />

Frequency<br />

3<br />

2<br />

1<br />

0<br />

3<br />

2<br />

1<br />

Median<br />

0.053 min -1<br />

0 0.04 0.08 0.12 0.16<br />

Reduction rate (min -1 )<br />

Tumor+DEM<br />

Median<br />

0.034 min -1<br />

0<br />

0 0.04<br />

0.08 0.12 0.16<br />

Yamada et al Acta Radiol (2002)<br />

Reduction rate (min -1 )

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