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The Physical Effects of Bubbles and Cavitation in High Intensity ...

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What Happens if the Tissue Gets Too<br />

Hot Too Quickly?<br />

Lesion formation <strong>in</strong> a gel<br />

<br />

<br />

LHS: side light<strong>in</strong>g<br />

RHS: back light<strong>in</strong>g<br />

3.5 MHz, 14 kW/cm 2 , 30 sec exposure<br />

Two separate runs <strong>in</strong> a low<br />

absorb<strong>in</strong>g phantom<br />

Boil<strong>in</strong>g leads to the formation <strong>of</strong> a<br />

malformed tadpole” lesion<br />

Inertial cavitation precedes boil<strong>in</strong>g,<br />

but the progression is extremely<br />

rapid (10’s s <strong>of</strong> msec)<br />

Khokhlova et al., J. Acoust Soc. Am.<br />

119, , 834-848, 2006<br />

30

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