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The Physical Effects of Bubbles and Cavitation in High Intensity ...

The Physical Effects of Bubbles and Cavitation in High Intensity ...

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Not Necessarily<br />

<br />

<br />

<br />

<br />

So long as you avoid boil<strong>in</strong>g temperatures, controlled <strong>in</strong>ertial<br />

cavitation can still <strong>of</strong>fer therapeutic value<br />

“Gentler” heat<strong>in</strong>g <strong>and</strong>/or non-thermal effects may be desirable<br />

<br />

<br />

Heat<strong>in</strong>g <strong>of</strong> sensitive regions<br />

Thrombolysis, , drug delivery, non-thermal tissue disruption<br />

Real-time feedback for tun<strong>in</strong>g the bubble field<br />

<br />

Control via duty cycle, pressure schedule, multiple frequencies<br />

Why isn’t t this currently be done <strong>in</strong> vivo?<br />

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<strong>The</strong>re are no cavitation nuclei <strong>in</strong> tissue!<br />

Nuclei are essential <strong>and</strong> may need to be <strong>in</strong>troduced externally<br />

(contrast agents, etc.)<br />

33

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