Collagen vascular disease in the lungs

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Background Has better prognosis than IPF: NSIP more common than UIP SSc-UIP has better prognosis than IPF Antoniou et al. ERJ 2009; 33: 882-96 Kim et al. Chest 2009; 136: 1397-405 Park et al. AJRCCM 2007; 175: 705-11
CXR Limited value Imaging HRCT Very sensitive (25-50% abnormal in diff series) NSIP pattern commonest Good correlation with pathology (although GGO can occur with fine fibrosis, esp. if traction bronchiectasis) Extent of disease (but not GGO) good predictor of outcome Often very limited disease (mean 13% of lung volume, esp. in lower 1/3 of lungs) HRCT: 50% of those with GGO HC over 5 yrs, rest stable Antoniou et al. ERJ 2009; 33: 882-96 Desai et al. Radiology 2004; 232: 560-7 Launay et al. J Rheum 2006; 33: 1789-801 Devaraj et al. Sem Resp Crit Care Med 2007; 28: 389-97
Page 1 and 2: COLLAGEN VASCULAR DISEASE IN THE LU
Page 3 and 4: Forms of Lung Disease in CVD • In
Page 5 and 6: ILD IN COLLAGEN VASCULAR DISEASE (C
Page 7 and 8: Antoniou et al. ERJ 2009; 33: 882-9
Page 9 and 10: NSIP: CXR • Bilateral • Fine re
Page 11 and 12: HRCT: UIP vs. NSIP
Page 13 and 14: Mean survivals of patients: HRCT di
Page 15: Background ILD common in SSc: 75% (
Page 19 and 20: Serial PFTs & Prognosis: IPF Bad Pr
Page 21 and 22: Prognostic Algorithm Used 215 SSc-I
Page 23 and 24: 6MWT & Prognosis: IPF • Safe •
Page 25 and 26: SSc: Exercise Testing CPEX has been
Page 27 and 28: Therapy 1) Prednisone ?? renal cris
Page 29 and 30: RHEUMATOID ARTHRITIS (RA)
Page 31 and 32: RA-ILD worse prognosis than other C
Page 33 and 34: PFTs Good at picking up lung diseas
Page 35 and 36: Therapy No randomised controlled tr
Page 37 and 38: ILD uncommon in SLE: Background •
Page 39 and 40: Lung Biopsy Not often done CIP: NSI
Page 41: Pulmonary Approach to CVD Patients

Collagen vascular disease in the lungs

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