Collagen vascular disease in the lungs

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Imaging UIP CXR Limited value HRCT Very sensitive (19-56% of RA) Good predictor of pathology Patterns: • UIP (commonest): peripheral reticular + HC • NSIP: reticular + GGO • OP (organising pneumonia): patchy GGO May see coexisting airways disease NSIP OP Antoniou et al. ERJ 2009; 33: 882-96 Akira et al. JCAT 1999; 23: 941-8 Tanaka et al. Radiology 2004; 232: 81-91 Devaraj et al. Sem Resp Crit Care Med 2007; 28: 389-97
PFTs Good at picking up lung disease • FVC • DLCO • most sensitive •
Page 1 and 2: COLLAGEN VASCULAR DISEASE IN THE LU
Page 3 and 4: Forms of Lung Disease in CVD • In
Page 5 and 6: ILD IN COLLAGEN VASCULAR DISEASE (C
Page 7 and 8: Antoniou et al. ERJ 2009; 33: 882-9
Page 9 and 10: NSIP: CXR • Bilateral • Fine re
Page 11 and 12: HRCT: UIP vs. NSIP
Page 13 and 14: Mean survivals of patients: HRCT di
Page 15 and 16: Background ILD common in SSc: 75% (
Page 17 and 18: CXR Limited value Imaging HRCT Very
Page 19 and 20: Serial PFTs & Prognosis: IPF Bad Pr
Page 21 and 22: Prognostic Algorithm Used 215 SSc-I
Page 23 and 24: 6MWT & Prognosis: IPF • Safe •
Page 25 and 26: SSc: Exercise Testing CPEX has been
Page 27 and 28: Therapy 1) Prednisone ?? renal cris
Page 29 and 30: RHEUMATOID ARTHRITIS (RA)
Page 31: RA-ILD worse prognosis than other C
Page 35 and 36: Therapy No randomised controlled tr
Page 37 and 38: ILD uncommon in SLE: Background •
Page 39 and 40: Lung Biopsy Not often done CIP: NSI
Page 41: Pulmonary Approach to CVD Patients

Collagen vascular disease in the lungs

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