Collagen vascular disease in the lungs

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Screening for Lung Disease in CVD Should be routine • lung disease in CVD very common (20-85% in diff diseases & series) • major prognostic role • can pick up early potentially treatable disease • to have baseline if using potentially toxic drugs Methods: • Clinical • Imaging (CXR, HRCT) • PFTs • Lung biopsy (TBLBx, SLBx)
Forms of Lung Disease in CVD • Interstitial (ILD) e.g. NSIP, UIP, LIP, DIP, AIP, OP • Airways e.g. bronchiectasis, bronchiolitis • Vascular e.g. pulm hypertension, PTE, alveolar haemorrhage • Pleural e.g. effusions, thickening • Muscular/diaphragmatic e.g. restriction, atelectasis, Shrinking Lung Syndrome
Page 1: COLLAGEN VASCULAR DISEASE IN THE LU
Page 5 and 6: ILD IN COLLAGEN VASCULAR DISEASE (C
Page 7 and 8: Antoniou et al. ERJ 2009; 33: 882-9
Page 9 and 10: NSIP: CXR • Bilateral • Fine re
Page 11 and 12: HRCT: UIP vs. NSIP
Page 13 and 14: Mean survivals of patients: HRCT di
Page 15 and 16: Background ILD common in SSc: 75% (
Page 17 and 18: CXR Limited value Imaging HRCT Very
Page 19 and 20: Serial PFTs & Prognosis: IPF Bad Pr
Page 21 and 22: Prognostic Algorithm Used 215 SSc-I
Page 23 and 24: 6MWT & Prognosis: IPF • Safe •
Page 25 and 26: SSc: Exercise Testing CPEX has been
Page 27 and 28: Therapy 1) Prednisone ?? renal cris
Page 29 and 30: RHEUMATOID ARTHRITIS (RA)
Page 31 and 32: RA-ILD worse prognosis than other C
Page 33 and 34: PFTs Good at picking up lung diseas
Page 35 and 36: Therapy No randomised controlled tr
Page 37 and 38: ILD uncommon in SLE: Background •
Page 39 and 40: Lung Biopsy Not often done CIP: NSI
Page 41: Pulmonary Approach to CVD Patients

Collagen vascular disease in the lungs

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