Collagen vascular disease in the lungs
Collagen vascular disease in the lungs
Collagen vascular disease in the lungs
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Lung Biopsy<br />
Seldom needed<br />
HRCT predictive of pathology & prognosis<br />
May do if atypical or suspect OP:<br />
Plugs of loose proliferat<strong>in</strong>g granulation<br />
tissue (“Masson bodies”) with<strong>in</strong> lumen of<br />
bronchioles (“bronchiolitis obliterans”) &<br />
extend<strong>in</strong>g <strong>in</strong>to alveolar ducts & spaces<br />
(“organis<strong>in</strong>g pneumonia”)<br />
Patchy distribution (often peribronchial)<br />
Normal lung architecture<br />
Antoniou et al. ERJ 2009; 33: 882-96
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