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Cryobiology and cryopreservation of human gametes and ... - eshre

Cryobiology and cryopreservation of human gametes and ... - eshre

Cryobiology and cryopreservation of human gametes and ... - eshre

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General principles<br />

Outline<br />

Safety margins: reproducibility <strong>and</strong> consistency<br />

Theoretical models <strong>and</strong> margins for improvements<br />

Safety <strong>of</strong> liquid nitrogen storage<br />

Overview <strong>of</strong> cryodamage<br />

Timeline <strong>of</strong> slow freezing: progressive improvement<br />

over time<br />

Clinical efficiency<br />

How to measure clinical efficiency<br />

Factors (age, protocol, processing timing)<br />

Performance in vitro <strong>and</strong> in vivo <strong>of</strong> frozen oocytes (vs. frozen<br />

embryos <strong>and</strong> vitrified oocytes)<br />

Health <strong>of</strong> children

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