FEMLAB - KTH

5.9 Results
In Figure 5.2, concentrations inside the cytoplasm with time, are compared to the
in vitro results. The concentrations from the in vitro experiments were taken only
at a limited number of instants because it is a very difficult task. The scanty dots
represent concentrations from in vitro experiments, while the graphs are from the
simulations. It is not the actual concentrations which are plotted here, but the percentage,
where the maximum is set to 100 %. Overall, the patterns are similar. The
differences seen might be explained by that the molecular dynamics within the cell
is more complex than we assume in our model.
Figure 5.2. C, B and U in cytoplasm plotted with time
Plots of the concentration of C in the extracellular solution have been compared
to similar plots obtained experimentally by the researchers at K.I. It shows the half
life of C. Please see Figure 5.3.
Laboratory experiments showed that the half life of the substrate C in the solution
was about 63 seconds. The plot in Figure 5.2 obtained from the FEMLAB simulation
depicts a half-life of 60 seconds. This is close enough.
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