View Presentation Slides - PCSS-O

More documents

Recommendations

Info

Buprenorphine’s Unique Properties • Partial Agonist/Antagonist: has better safety profile – less respiratory depression • Highest affinity for the opioid receptor: will replace a pure agonist and even antagonist off the receptor • Long half-life – will bind the receptor for long period – elimination ½ life is ~ 37 hrs. • Has no oral bioavailability - its use in opioid dependence is the
The Use of Buprenorphine/Naloxone to treat opioid dependence • Buprenorphine/Naloxone: In 2002, Drug Abuse Treatment Act approved sublingual formulations of buprenorphine for treating opioid addiction Effectively treats opioid addiction by reducing illicit opioid use, improving treatment retention (55- 60%) 9 , and increasing negative urine toxicology screens 10 Physicians fulfilling certification requirements can apply to Center for Substance Abuse Treatment for a special waiver to prescribe.
Page 1 and 2: Patricia Pade, MD University of Col
Page 3 and 4: Objectives • To provide a brief o
Page 5 and 6: Chronic Pain • 116 million people
Page 7 and 8: Opioid Use • Use of opioids has i
Page 9 and 10: Fatal Drug Poisoning • Between 19
Page 11 and 12: Opioid Pharmacology: How do these M
Page 13 and 14: • Tolerance: Repeated Dosing: Opi
Page 15 and 16: Brief pharmacology overview: full o
Page 17: Brief pharmacology overview: opioid
Page 21 and 22: The Problem for Veterans
Page 23 and 24: Improvement Change: Creation of Co-
Page 25 and 26: Patient population • Referrals fr
Page 27 and 28: Initial Evaluation A. PAIN Detailed
Page 29 and 30: Buprenorphine induction process •
Page 31 and 32: Study participants Participant Data
Page 33 and 34: Months Average duration of opioid u
Page 35 and 36: Number Number Number 60 40 Co-morbi
Page 37 and 38: Adjuvant Medications Na and Interve
Page 39 and 40: Ongoing monitoring for compliance
Page 41 and 42: 93/143 patients remained in treatme
Page 43 and 44: Conclusions 11. Patients with co-oc
Page 45 and 46: Office Based Opioid Treatment: Bupr
Page 47: References 1. Institute of Medicine

View Presentation Slides - PCSS-O

Create successful ePaper yourself

Delete template?

Save as template?